The median nerve is a mixed nerve that arises from the brachial plexus and innervates parts of the arm, forearm, and hand. It is susceptible to compression injuries at the carpal tunnel in the wrist (carpal tunnel syndrome) and between the heads of the pronator teres muscle in the elbow (pronator syndrome). Carpal tunnel syndrome commonly causes pain, numbness, and tingling in the hand and can lead to muscle atrophy if not treated. Non-surgical treatments include splinting and injections while surgical decompression of the carpal tunnel is also an option.