This document provides guidelines for managing patients with medical disorders during orthodontic treatment planning and care. It discusses important considerations for various conditions including cardiovascular diseases like infective endocarditis and hypertension, hematological diseases like bleeding disorders and sickle cell anemia, respiratory diseases like asthma and cystic fibrosis, and other conditions. Key recommendations include thoroughly reviewing medical histories, maintaining good oral hygiene, minimizing risks and stresses, consulting physicians, and tailoring orthodontic forces and procedures to each patient's specific needs and health status.