Mining and communicating biomedical knowledge
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The document discusses mining and communicating biomedical knowledge. It covers three main parts: 1) complex regulation of cell cycles and protein interactions over time, 2) exponential growth of published research and challenges of knowledge discovery, and 3) changes in scientific publishing from pre-publication peer review to open access and post-publication peer review on the internet.
Mining and communicating biomedical knowledge
- 1. Mining and communicating biomedical knowledge Lars Juhl Jensen
- 2. Part 1 complex regulation
- 5. microarrays
- 7. time courses
- 8. Gauthier et al., Nucleic Acids Research , 2007
- 10. Jensen & Bork, Science , 2008
- 11. temporal network
- 12. de Lichtenberg, Jensen et al., Science , 2005
- 14. de Lichtenberg, Jensen et al., Cell Cycle , 2007
- 16. individual genes
- 17. Jensen, Jensen, de Lichtenberg et al., Nature , 2006
- 19. Jensen, Jensen, de Lichtenberg et al., Nature , 2006
- 21. Part 2 buried knowledge
- 25. some things are constant
- 27. ~45 seconds per paper
- 28. computer
- 29. as smart as a dog
- 30. teach it specific tricks
- 34. new uses for old drugs
- 35. Campillos & Kuhn et al., Science , 2008
- 37. Pafilis, O’Donoghue, Jensen et al., Nature Biotechnology , 2009
- 39. >10 km <10 hours
- 41. Part 3 science communication
- 42. ~150 years ago
- 44. today
- 53. issues
- 56. the world has changed
- 58. internet economy
- 61. open access
- 62. free to download
- 63. free to reuse
- 66. publish first
- 68. filter later
- 72. Brumfiel, Nature , 2009
- 73. Saunders et al., PLoS Computational Biology , 2009
- 75. Thanks Past and present colleagues at Center for Biological Sequence Analysis European Molecular Biology Laboratory Novo Nordisk Foundation Center for Protein Research The bloggers who made it happen at ISMB The Lundbeck Foundation All of you who are here today!