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Organization of Motor System
Spinal Motor Neuron
Motor Unit
Neuromuscular Junction
Motor system overview 2011
Motor system overview 2011
Types of Muscle Contraction
Muscle Spindle
Stretch Reflex
Motor system overview 2011
Golgi Tendon Organ
Feedback Inhibition: Golgi Tendon Organ
Withdrawal Reflex
Withdrawal and Crossed Extensor Reflex
Alpha and gamma motor neurons are coactivated during voluntary movements
Spinal Animal
Cat hind limb activity during stepping
Locomotor Center in Cat
Motor Cortex in precise stepping
Locomation
Motor cortical center
Functional Organization of the Primary Motor Cortex
Corticospinal Pathway
CorticoRubrospinal Pathway
Convergence of Motor Control on the Anterior Motor Neuron
Corticomotoneuronal (CM) cell is active depends on the motor task
Activity in Individual Neurons of the Primary Motor Cortex Is Related to Muscle Force and Direction of Movement
A set-related neuron in the dorsal premotor area becomes active while the monkey prepares to make a movement to the left
Motor Cortical Cell Firing with Force Generated
Different areas of cortex are activated during simple, complex, and imagined sequences of finger movements (Xenon PET)
Cell activity in the motor cortex depends on whether a sequence of movements is guided by visual cues or by prior training
The visuomotor transformations required for reaching and grasping involve two different pathways
Individual neurons in the ventral premotor area fire during specific hand actions only
Motor planning
Mirror NeuronsA. Activity in the neuron as the monkey observes another monkey make a precision group.B. Activity in the same neuron as the monkey observes the human experimenter make the precision grip.C. Activity in the same neuron as the monkey itself performs a precision grip. (From Rizzolottiet al 1996.)
SummaryPrimary Motor Cortex:Codes force and direction of movementSpinal motor neuron are directly under control for precise movement.Dorsal Premotor CortexMovement related neuron encodes sensorimotor transformation for visual and sensory cueFire before movementVentral Premotor CortexEncodes learned motor act fire before movementAll cortical neurons are adaptable and plastic
Basal Ganglia
Functional organization of BG
Motor Component of Basal Ganglia
Basal Ganglia in Executing Patterns of Motor Activity— The Putamen Circuit
Cognitive Control of Sequences of Motor Patterns—The Caudate Circuit
Neurotransmitters of BG
Function of BGVoluntary movementInitiation of movementControl of ramp movementChange from one pattern to otherProgramming and correcting movement while in progress (thalamocortical circuts)Postural controlRighting reflexAutomatic associated movement (walking)Control of muscle toneReticulospinal Vestibulospinal
Cerebellum
Functional organization of cerebellum
Afferent Pathway of Brain
Spinocerebellar pathway
Output Signals from the Cerebellum
Neocerebellum
Vestibulocerebellum
The spinocerebellum contains two somatotopic neural maps of the body
Neuronal Circuit of the Functional Unit
Motor system overview 2011
Control of voluntary movementExecutionPlanningBasal GangliaAssociation cortexPremotor + Motor cortexMovementIdeaLateral cerebellumIntermediate Cerebellum

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Motor system overview 2011