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My Experiences
       Quantifying My Sleep States

                   Informal Seminar
              de la Iglesia and Opp Labs
              University of Washington
                      Seattle, WA
                     April 17, 2012
                      Dr. Larry Smarr
Director, California Institute for Telecommunications and
                 Information Technology
                Harry E. Gruber Professor,
      Dept. of Computer Science and Engineering
          Jacobs School of Engineering, UCSD
           Follow me at http://lsmarr.calit2.net
I Have Spent Ten Years
     Quantifying My Body




www.technologyreview.com/biomedicine/39636
BodyMedia Sensors Measures Acceleration, Skin Temperature,
        Skin Heat Flux, and Galvanic Skin Response

www.bodymedia.com



                        Elliptical   Gardening   Up and Down House Steps




                                                25 Week Average:
                                            2473 Calories Burned/Day
                                      1:19 hr Physical Activity/Day (>3 METs)
                                           6887 Steps/Day (~3.4 Miles)


                    Measure Quantity and Quality of Sleep




                           25 Week Ave: 6:51 hrs with 81% Efficiency
Published Comparison of BodyMedia
         with Sleep Lab Polysomnography (PSG)
• 27 participants (Mean age = 28.7 years, 16 women) underwent
  PSG recordings while wearing the armband.
• PSG and armband data were scored in 20-second epochs.
• BodyMedia's sleep algorithm was developed using techniques
  from statistical machine learning.
• The algorithm correctly identified 93% of all sleep epochs, and
  83% of all wakefulness epochs, for an overall epoch-by-epoch
  accuracy of 89%.
• The algorithm correctly identified 65% of all NREM sleep
  epochs (vs. 43.9% by chance), and 45.6% of all REM sleep
  epochs (vs.13.9% by chance), for an epoch-by-epoch accuracy
  of 70% (vs. 39% by chance).


              www.bodymedia.com/Professionals/Key-
              Publications/Abstract-presented-at-SLEEP-2006-
              20th-Anniversary-Meeting-of-the-AOSS-2006
Quantifying My Sleep Pattern Using Zeo -
Surprisingly About Half My Sleep is REM!




     REM is Normally 20% of Sleep     An Infant Typically
    Mine is Between 45-65% of Sleep    Has 50% REM
I Have Worn A Zeo
   for 400 Nights



          MIT Graduate student Ian Eslick
On the Road Zeo Solution:
Link Headband to Android Smartphone
Published Comparison of Zeo with
 Sleep Lab Polysomnography (PSG)
                                                 Shambroom JR, Johnstone
                                                 J, Fabregas SE. Evaluation
                                                of Portable Monitor for Sleep
                                                   Staging. Sleep. 2009;32
                                                   (Suppl.): A386. Abstract
                                                             1182.


                    •Sleep in the laboratory at the participant’s habitual
                    bedtime
                    •Concurrent measurement of PSG and WS

                    •PSG data collected with Cadwell Easy II PSG,
                    sampled at 200 samples per second
                    •WS data were sampled at 128 samples per second

                    •Sleep records were scored blinded to WS
                             by 2 trained technicians (M1 and M2)
                    according to Rechtschaffen & Kales
                    •Sleep records were scored automatically by the WS

www.myzeo.com/sleep/sites/default/files/Shambroom%2C%20
Johnstone%2C%20Fabregas_Validation_2009_APSS_poster.pdf
Recent Paper Details Comparing Zeo Accuracy
        vs. Sleeplab and Actigraphy
How the ZQ is Computed:
A Typical Night with ZQ=100
My ZQ Can Vary
By a Factor of Two
My Total Sleep Can
Vary by a Factor of 2
My Deep Sleep Duration
Can Vary by a Factor of 3
My Average ZQ is About 100 --
ZQ Average is 66 for Males in Their 60s
I Have Over Twice the REM Sleep of
             a Normal Male in Their 60s
 Average                   Normal Person                    Me
                            In Their 60s                   Age 62




   ZQ                            66                         100


Total Sleep                    6.3 hrs                     8.5 hrs


   REM                         1.9 hrs                     4.5 hrs


  Deep                         41 min                      40 min


  Wake                         40 min                      15 min



              LS Values From Ten Days 8/31/11 to 9/10/11
                           Source: Zeo.com
I Have a Fairly Stable Amount of Sleep:
           Monthly Averages
Possible Weak Seasonal Effect
  On Quantity of Deep Sleep
Zeo Lets One Couple
Sleep Journal Entries to Sleep Data
I Have a Fairly Consistent Sleep Architecture:
A Few REM Blocks Early, Then a “Wall of REM”




                  Source: Zeo 2011
One of My Highest ZQ and % REM:
    Night After Colonoscopy
Five Nights in a Row with Low REM 36-43%
  Three Weeks After Starting Prednisone
Night #2 With Low REM
Night #3 With Low REM
Night #4 With Low REM
Night #5 With Low REM
Trip La Jolla to Perth, Australia
    Takes Roughly 4 Days for REM to Re-adjust to ~50%
                  All Graphs Are Aligned to La Jolla Pacific Time Zone



8/2/11
                                                                         ZQ      89
La Jolla
                                                                         Total Z 7:35
                                                                         REM     50%



                                                                         ZQ      71
8/6/11                                                                   Total Z 7:16
Qantas LAX-Brisbane                                                      REM     29%




8/9/11                 ZQ      91
Perth                  Total Z 8:12
                       REM     61%
Return Trip Perth to La Jolla
Takes 4 Days for REM to Re-establish ~50%
          All Graphs Are Aligned to La Jolla Pacific Time Zone


8/13/11            ZQ      63
Perth              Total Z 5:54
                   REM     47%




                                                                 ZQ      83
                                                    8/16/11
                                                                 Total Z 7:09
                                                    La Jolla
                                                                 REM     28%


                                                                 ZQ      117
                                                     8/19/11
                                                                 Total Z 9:52
                                                     La Jolla
                                                                 REM     51%
Zeo Does Work With Researchers and Educators




We recognize the incredible importance of researchers and
educators, and also the challenges that they face in
continuing their work.

In order to do our part, we often support and provide special
pricing for vital research and education efforts.




                 www.myzeo.com/sleep/additional-research
Zeo Supports Open Platform Developers:
         Android Mobile API




       https://github.com/zeoeng/zeo-android-api
Zeo Has a Developer API




   http://developers.myzeo.com/

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My Experiences Quantifying My Sleep States

  • 1. My Experiences Quantifying My Sleep States Informal Seminar de la Iglesia and Opp Labs University of Washington Seattle, WA April 17, 2012 Dr. Larry Smarr Director, California Institute for Telecommunications and Information Technology Harry E. Gruber Professor, Dept. of Computer Science and Engineering Jacobs School of Engineering, UCSD Follow me at http://lsmarr.calit2.net
  • 2. I Have Spent Ten Years Quantifying My Body www.technologyreview.com/biomedicine/39636
  • 3. BodyMedia Sensors Measures Acceleration, Skin Temperature, Skin Heat Flux, and Galvanic Skin Response www.bodymedia.com Elliptical Gardening Up and Down House Steps 25 Week Average: 2473 Calories Burned/Day 1:19 hr Physical Activity/Day (>3 METs) 6887 Steps/Day (~3.4 Miles) Measure Quantity and Quality of Sleep 25 Week Ave: 6:51 hrs with 81% Efficiency
  • 4. Published Comparison of BodyMedia with Sleep Lab Polysomnography (PSG) • 27 participants (Mean age = 28.7 years, 16 women) underwent PSG recordings while wearing the armband. • PSG and armband data were scored in 20-second epochs. • BodyMedia's sleep algorithm was developed using techniques from statistical machine learning. • The algorithm correctly identified 93% of all sleep epochs, and 83% of all wakefulness epochs, for an overall epoch-by-epoch accuracy of 89%. • The algorithm correctly identified 65% of all NREM sleep epochs (vs. 43.9% by chance), and 45.6% of all REM sleep epochs (vs.13.9% by chance), for an epoch-by-epoch accuracy of 70% (vs. 39% by chance). www.bodymedia.com/Professionals/Key- Publications/Abstract-presented-at-SLEEP-2006- 20th-Anniversary-Meeting-of-the-AOSS-2006
  • 5. Quantifying My Sleep Pattern Using Zeo - Surprisingly About Half My Sleep is REM! REM is Normally 20% of Sleep An Infant Typically Mine is Between 45-65% of Sleep Has 50% REM
  • 6. I Have Worn A Zeo for 400 Nights MIT Graduate student Ian Eslick
  • 7. On the Road Zeo Solution: Link Headband to Android Smartphone
  • 8. Published Comparison of Zeo with Sleep Lab Polysomnography (PSG) Shambroom JR, Johnstone J, Fabregas SE. Evaluation of Portable Monitor for Sleep Staging. Sleep. 2009;32 (Suppl.): A386. Abstract 1182. •Sleep in the laboratory at the participant’s habitual bedtime •Concurrent measurement of PSG and WS •PSG data collected with Cadwell Easy II PSG, sampled at 200 samples per second •WS data were sampled at 128 samples per second •Sleep records were scored blinded to WS by 2 trained technicians (M1 and M2) according to Rechtschaffen & Kales •Sleep records were scored automatically by the WS www.myzeo.com/sleep/sites/default/files/Shambroom%2C%20 Johnstone%2C%20Fabregas_Validation_2009_APSS_poster.pdf
  • 9. Recent Paper Details Comparing Zeo Accuracy vs. Sleeplab and Actigraphy
  • 10. How the ZQ is Computed: A Typical Night with ZQ=100
  • 11. My ZQ Can Vary By a Factor of Two
  • 12. My Total Sleep Can Vary by a Factor of 2
  • 13. My Deep Sleep Duration Can Vary by a Factor of 3
  • 14. My Average ZQ is About 100 -- ZQ Average is 66 for Males in Their 60s
  • 15. I Have Over Twice the REM Sleep of a Normal Male in Their 60s Average Normal Person Me In Their 60s Age 62 ZQ 66 100 Total Sleep 6.3 hrs 8.5 hrs REM 1.9 hrs 4.5 hrs Deep 41 min 40 min Wake 40 min 15 min LS Values From Ten Days 8/31/11 to 9/10/11 Source: Zeo.com
  • 16. I Have a Fairly Stable Amount of Sleep: Monthly Averages
  • 17. Possible Weak Seasonal Effect On Quantity of Deep Sleep
  • 18. Zeo Lets One Couple Sleep Journal Entries to Sleep Data
  • 19. I Have a Fairly Consistent Sleep Architecture: A Few REM Blocks Early, Then a “Wall of REM” Source: Zeo 2011
  • 20. One of My Highest ZQ and % REM: Night After Colonoscopy
  • 21. Five Nights in a Row with Low REM 36-43% Three Weeks After Starting Prednisone
  • 22. Night #2 With Low REM
  • 23. Night #3 With Low REM
  • 24. Night #4 With Low REM
  • 25. Night #5 With Low REM
  • 26. Trip La Jolla to Perth, Australia Takes Roughly 4 Days for REM to Re-adjust to ~50% All Graphs Are Aligned to La Jolla Pacific Time Zone 8/2/11 ZQ 89 La Jolla Total Z 7:35 REM 50% ZQ 71 8/6/11 Total Z 7:16 Qantas LAX-Brisbane REM 29% 8/9/11 ZQ 91 Perth Total Z 8:12 REM 61%
  • 27. Return Trip Perth to La Jolla Takes 4 Days for REM to Re-establish ~50% All Graphs Are Aligned to La Jolla Pacific Time Zone 8/13/11 ZQ 63 Perth Total Z 5:54 REM 47% ZQ 83 8/16/11 Total Z 7:09 La Jolla REM 28% ZQ 117 8/19/11 Total Z 9:52 La Jolla REM 51%
  • 28. Zeo Does Work With Researchers and Educators We recognize the incredible importance of researchers and educators, and also the challenges that they face in continuing their work. In order to do our part, we often support and provide special pricing for vital research and education efforts. www.myzeo.com/sleep/additional-research
  • 29. Zeo Supports Open Platform Developers: Android Mobile API https://github.com/zeoeng/zeo-android-api
  • 30. Zeo Has a Developer API http://developers.myzeo.com/