Neonicotinoids are a class of systemic insecticides related to nicotine. They are widely used globally due to their effectiveness against insects and low toxicity to mammals. However, research has shown they are highly toxic to bees even at low levels. Bees can be directly exposed through contaminated nectar or pollen or indirectly through dust from seed coating or honeydew from insects exposed to neonics. Both acute and chronic exposure has been shown to impair bee health and cause colony collapse disorder. Given bees play a key role in pollinating many important agricultural crops, protecting honeybee populations from neonicotinoids is important for global food security and agriculture.