This document discusses Node.js and its approach to handling input/output (I/O) operations in a non-blocking and asynchronous way. It notes that I/O operations like accessing the disk or network can be very slow, taking millions of cycles. Node.js addresses this by using an event-driven, asynchronous programming model where callbacks are used to handle the results of slow I/O operations without blocking the main thread. Examples are given to illustrate how Node.js handles database queries and HTTP requests asynchronously in a non-blocking way to improve performance compared to traditional synchronous approaches or other web servers.