OEE (Overall Equipment Effectiveness) is calculated by multiplying Availability, Performance, and Quality percentages. It is used to measure manufacturing equipment productivity. The document discusses how to calculate OEE for a single machine and a group of plants. It also outlines the six major types of losses that reduce OEE (Breakdowns, Setups, Small Stops, Reduced Speeds, Startup Rejects, Production Rejects) and methods to address them such as root cause analysis, SMED, and Six Sigma. World class OEE levels are listed as 85% which requires 90% Availability, 95% Performance, and 99.9% Quality.