Self-medication involves using medicines to treat minor ailments without medical supervision. It is commonly practiced worldwide and promoted by WHO in rural areas with limited access to healthcare. Over-the-counter (OTC) drugs are approved for self-medication to treat minor conditions. While OTC drugs provide convenience, their misuse can be dangerous. Some OTC drugs have been banned in India due to health risks, including Nimesulide for liver toxicity and cough syrups containing codeine due to addiction concerns. Community pharmacists should take responsibility for proper OTC use by patients through consultation and education.