This paper evaluates a solution to combat inter-carrier interference (ICI) in Orthogonal Frequency Division Multiplexing (OFDM) systems operating over doubly selective fading channels by combining channel estimation with ICI self-cancellation techniques. Simulation results demonstrate that this combined approach effectively reduces the impact of ICI, thereby improving OFDM system performance. The study includes empirical assessments under practical conditions utilizing a variety of fading channels.