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PEPTIC ULCER
BY THOUNAOJAM RINITA DEVI
peptic ulcer.pptx for nursing students..
INTRODUCTION
• Peptic ulcers are sores that develop in the
lining of the stomach, lower oesophagus, or
duodenum. They are usually formed as a
result of inflammation caused by the bacteria
H.pylori, as well as from erosion from
stomach Acids.
"Peptic" refers to pepsin: a stomach enzyme
that breaks down protein
An ulcer occurs when the lining of these
organs is corroded by acidic digestive
juices secreted by the stomach cells.
Peptic ulcers are a fairly common health
problem.
ANATOMY AND PHYSIOLOGY
LAYERS OF STOMACH
DEFINITION
• A peptic ulcer is an excavation formed in
the mucosal wall of the stomach, pylorus,
duodenum (beginning of the small
intestine), or oesophagus.
• It is frequently referred to as a gastric,
duodenal, or oesophageal ulcer,
depending on its location. It is caused by
the erosion of a circumscribed area of
mucous membrane.
• Peptic ulcers are more likely to be in the
duodenum than in the stomach. They tend
to occur singly, but there may be several
present at one time.
• Chronic ulcers usually occur in the lesser
curvature of the stomach, near the
pylorus.
TYPES OF PEPTIC ULCER
GASTRIC ULCERS
Gastric ulcers are sores in the lining of the
stomach or small intestine. They occur
when the protective mucus that lines the
stomach becomes ineffective. The
stomach produces a strong acid to help
digest food and protect against microbes.
CONTD...
• To protect the tissues of the body from
this acid, it also secretes a thick layer of
mucus. If the mucus layer is worn away
and stops functioning effectively, the acid
can damage the stomach tissue, causing
an ulcer.
OESOPHAGEAL ULCERS
An oesophageal ulcer is a type of peptic
ulcer that develops in the lining of the
oesophagus, the tube that connects the
throat to the stomach. Oesophageal ulcers
occur when the layer of mucus, which
lines and protects the gastrointestinal
tract, wears away
DUODENAL ULCERS
Duodenal ulcers develop in the lining of the
duodenum, which is the upper part of the
small intestine.
CAUSES
• Different factors can cause the
lining of the stomach, the
oesophagus, and the small
intestine to break down. These
include:
• Helicobacter pylori (H. pylori),
a type of bacteria that can cause
a stomach infection and
inflammation.
• Taking or frequent use of non
steroidal antiinflammatory
drugs (NSAIDs) , aspirin
CONTD...
( Bayer) and ibuprofen (Advil) can increase
the risk of peptic ulcer disease by four
times compared to non-users (in women
and people over the age of 60 years).
• Other causes of peptic ulcer disease
include gastric ischemia, drugs, metabolic
disturbances, cytomegalovirus (CMV),
upper abdominal radiotherapy, Crohn's
disease, and vasculitis..
RISK FACTORS
• Smoking
• Drinking too much alcohol
• Radiation therapy
• Stomach cancer
• Spicy food
• Having other family members with peptic
ulcer disease
Pathophysiology
SIGN AND SYMPTOM
The most common symptom of a peptic
ulcer is burning abdominal pain that extends
from the navel to the chest, which can range
from mild to severe..Small peptic ulcers
may not produce any symptoms in the early
phases.
CONTD..
Other common signs of a peptic ulcer
include:
• Burning stomach pain that:
- May wake a person up from sleeping
- May last a few minutes or many hours
- Is worse on an empty stomach but better
after eating or drinking
- Feels better after taking antacids
• Nausea and vomiting
• Lack of hunger
• Unexplained weight loss
• Bloating
• Feeling of fullness
• Heartburn
Ulcers can cause bleeding. It is rare but heavier
bleeding can cause:
- Bloody or black, tarry stools
- Vomiting that looks like coffee grounds or blood
DIAGNOSTIC EVALUATION
Two types of tests are available to diagnose a
peptic ulcer. They are called upper endoscopy
and upper gastrointestinal (GI) series.
Upper endoscopy
• In this procedure, doctor inserts a long tube with a
camera down to throat and into the stomach and small
intestine to examine the area for ulcers.
• Not all cases require an upper endoscopy.
• However, this procedure is recommended for people
with a higher risk of stomach cancer. This includes
people over the age of 45, as well as people who
experience:
-anaemia
- weight loss
- gastrointestinal bleeding
- difficulty swallowing
peptic ulcer.pptx for nursing students..
Upper GI series
• If the person doesn’t have difficulty in
swallowing and have a low risk of
stomach cancer, doctor may recommend
an upper GI test instead. For this
procedure, the person will drink a thick
liquid called barium (barium swallow).
Then a technician will take an X-ray
• of stomach, oesophagus, and small
intestine of the person. The liquid will
make it possible for the doctor to view
and treat the ulcer.
• Because H. pylori is a cause of peptic
ulcers, doctor will also run a test to check
for this infection in the stomach.
peptic ulcer.pptx for nursing students..
• X-ray : it helps to detect abnormalities in
esophagus stomach and small intestine
• Endoscopy : Performed to examine ulcers
• Biopsy : during endoscopy ,small tissue
samples are removed to examine peptic ulcers.
It can also help to identify whether H.pylori in
stomach is present or not
• CBC: A CBC with decreased hematocrit and
hemoglobin values may indicates bleeding
• Stool antigen test : Performed to observe
protiens present in the stool related to
H.pylori
• Gastroscopy: Performed to obsereve
inside patient’s stomach and duodenum
Management
• Treatment will depend on the underlying
causes of the ulcer. If the tests show that
person has an H. pylori infection, then doctor
will prescribe a combination of medication.
• The person will have to take the medications
for up to two weeks. The medications include
antibiotics to help kill infections and proton
pump inhibitors (PPIs) to help reduce stomach
acid.
• Antacids in combination with cimetidine
(Tagamet) or ranitidine (Zantac) for
treatment of stress ulcer and for
prophylactic use.
• H2-receptor antagonists acid blockers
like ranitidine (Zantac) or famotidine
(Pepcid) can also reduce stomach acid
and ulcer pain. These medications are
available as a prescription and also over
the counter in lower doses.
• Mucosal barrier fortifiers : sucralfat
(Carafate) which will coat the stomach
and reduce symptoms of peptic ulcers.
Surgical management
Antrectomy
Billroth -1( Gastroduodenostomy) : It
involves the removal of lower portion of
antrum,pylorus and small portion of
duoddenum
Billroth -2 ( Gastrojejunostomy): It
involves removal of stomach
peptic ulcer.pptx for nursing students..
Pyloroplasty
During this surgical procedure , an incision
is made in the lower stomach (Pylorus) of
Patients
It is transversally sutured closed to widen
the outlet and relaxing the muscles
Delayed gastric emptying is the most
common complication of the surgical
treatment
peptic ulcer.pptx for nursing students..
Vagotomy
• It performed under general anesthesia,incision
is made in the patient’s abdomen and vagus
nerve is located. Either the trunk or branches
leading to stomach are cut. Then, the
abdominal muscles are sewn back together and
skin is closed with sutures.
Types of vagotomy
 Truncal or total abdominal vagotomy:
• Total gastric or selective vagotomy
• Proximal gastric or highly selective
vagotomy
peptic ulcer.pptx for nursing students..
Nursing management
Nursing assessment :
• Assess pain and methods used to relieve it;
take a thorough history, including a 72-hour
food intake history.
• If patient has vomited, determine whether
emesis is bright red or coffee ground in
appearance. This helps identify source of the
blood.
• Ask patient about usual food habits, alcohol,
smoking, medication use (NSAIDs), and level of
tension or nervousness.
• Ask how patient expresses anger (especially at work
and with family), and determine whether patient is
experiencing occupational stress or family problems.
• Obtain a family history of ulcer disease.
• Assess vital signs for indicators of anaemia
(tachycardia, hypotension).
• Assess for blood in the stools with an occult blood
test.
• Palpate abdomen for localized tenderness
Nursing Diagnoses
• Acute pain related to the effect of gastric acid
secretion on damaged tissue
• Anxiety related to coping with an acute
disease
• Imbalanced nutrition related to changes in diet
• Deficient knowledge about preventing
symptoms and managing the condition
Complications
• Hemorrhage: upper GI
• Perforation
• Penetration
• Pyloric obstruction (gastric outlet
obstruction)
THANK YOU

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peptic ulcer.pptx for nursing students..

  • 3. INTRODUCTION • Peptic ulcers are sores that develop in the lining of the stomach, lower oesophagus, or duodenum. They are usually formed as a result of inflammation caused by the bacteria H.pylori, as well as from erosion from stomach Acids. "Peptic" refers to pepsin: a stomach enzyme that breaks down protein
  • 4. An ulcer occurs when the lining of these organs is corroded by acidic digestive juices secreted by the stomach cells. Peptic ulcers are a fairly common health problem.
  • 7. DEFINITION • A peptic ulcer is an excavation formed in the mucosal wall of the stomach, pylorus, duodenum (beginning of the small intestine), or oesophagus. • It is frequently referred to as a gastric, duodenal, or oesophageal ulcer, depending on its location. It is caused by the erosion of a circumscribed area of mucous membrane.
  • 8. • Peptic ulcers are more likely to be in the duodenum than in the stomach. They tend to occur singly, but there may be several present at one time. • Chronic ulcers usually occur in the lesser curvature of the stomach, near the pylorus.
  • 10. GASTRIC ULCERS Gastric ulcers are sores in the lining of the stomach or small intestine. They occur when the protective mucus that lines the stomach becomes ineffective. The stomach produces a strong acid to help digest food and protect against microbes.
  • 11. CONTD... • To protect the tissues of the body from this acid, it also secretes a thick layer of mucus. If the mucus layer is worn away and stops functioning effectively, the acid can damage the stomach tissue, causing an ulcer.
  • 12. OESOPHAGEAL ULCERS An oesophageal ulcer is a type of peptic ulcer that develops in the lining of the oesophagus, the tube that connects the throat to the stomach. Oesophageal ulcers occur when the layer of mucus, which lines and protects the gastrointestinal tract, wears away
  • 13. DUODENAL ULCERS Duodenal ulcers develop in the lining of the duodenum, which is the upper part of the small intestine.
  • 14. CAUSES • Different factors can cause the lining of the stomach, the oesophagus, and the small intestine to break down. These include: • Helicobacter pylori (H. pylori), a type of bacteria that can cause a stomach infection and inflammation. • Taking or frequent use of non steroidal antiinflammatory drugs (NSAIDs) , aspirin
  • 15. CONTD... ( Bayer) and ibuprofen (Advil) can increase the risk of peptic ulcer disease by four times compared to non-users (in women and people over the age of 60 years). • Other causes of peptic ulcer disease include gastric ischemia, drugs, metabolic disturbances, cytomegalovirus (CMV), upper abdominal radiotherapy, Crohn's disease, and vasculitis..
  • 16. RISK FACTORS • Smoking • Drinking too much alcohol • Radiation therapy • Stomach cancer • Spicy food • Having other family members with peptic ulcer disease
  • 18. SIGN AND SYMPTOM The most common symptom of a peptic ulcer is burning abdominal pain that extends from the navel to the chest, which can range from mild to severe..Small peptic ulcers may not produce any symptoms in the early phases.
  • 19. CONTD.. Other common signs of a peptic ulcer include: • Burning stomach pain that: - May wake a person up from sleeping - May last a few minutes or many hours - Is worse on an empty stomach but better after eating or drinking - Feels better after taking antacids
  • 20. • Nausea and vomiting • Lack of hunger • Unexplained weight loss • Bloating • Feeling of fullness • Heartburn Ulcers can cause bleeding. It is rare but heavier bleeding can cause: - Bloody or black, tarry stools - Vomiting that looks like coffee grounds or blood
  • 21. DIAGNOSTIC EVALUATION Two types of tests are available to diagnose a peptic ulcer. They are called upper endoscopy and upper gastrointestinal (GI) series.
  • 22. Upper endoscopy • In this procedure, doctor inserts a long tube with a camera down to throat and into the stomach and small intestine to examine the area for ulcers. • Not all cases require an upper endoscopy. • However, this procedure is recommended for people with a higher risk of stomach cancer. This includes people over the age of 45, as well as people who experience: -anaemia - weight loss - gastrointestinal bleeding - difficulty swallowing
  • 24. Upper GI series • If the person doesn’t have difficulty in swallowing and have a low risk of stomach cancer, doctor may recommend an upper GI test instead. For this procedure, the person will drink a thick liquid called barium (barium swallow). Then a technician will take an X-ray
  • 25. • of stomach, oesophagus, and small intestine of the person. The liquid will make it possible for the doctor to view and treat the ulcer. • Because H. pylori is a cause of peptic ulcers, doctor will also run a test to check for this infection in the stomach.
  • 27. • X-ray : it helps to detect abnormalities in esophagus stomach and small intestine • Endoscopy : Performed to examine ulcers • Biopsy : during endoscopy ,small tissue samples are removed to examine peptic ulcers. It can also help to identify whether H.pylori in stomach is present or not • CBC: A CBC with decreased hematocrit and hemoglobin values may indicates bleeding
  • 28. • Stool antigen test : Performed to observe protiens present in the stool related to H.pylori • Gastroscopy: Performed to obsereve inside patient’s stomach and duodenum
  • 29. Management • Treatment will depend on the underlying causes of the ulcer. If the tests show that person has an H. pylori infection, then doctor will prescribe a combination of medication. • The person will have to take the medications for up to two weeks. The medications include antibiotics to help kill infections and proton pump inhibitors (PPIs) to help reduce stomach acid.
  • 30. • Antacids in combination with cimetidine (Tagamet) or ranitidine (Zantac) for treatment of stress ulcer and for prophylactic use.
  • 31. • H2-receptor antagonists acid blockers like ranitidine (Zantac) or famotidine (Pepcid) can also reduce stomach acid and ulcer pain. These medications are available as a prescription and also over the counter in lower doses. • Mucosal barrier fortifiers : sucralfat (Carafate) which will coat the stomach and reduce symptoms of peptic ulcers.
  • 32. Surgical management Antrectomy Billroth -1( Gastroduodenostomy) : It involves the removal of lower portion of antrum,pylorus and small portion of duoddenum Billroth -2 ( Gastrojejunostomy): It involves removal of stomach
  • 34. Pyloroplasty During this surgical procedure , an incision is made in the lower stomach (Pylorus) of Patients It is transversally sutured closed to widen the outlet and relaxing the muscles Delayed gastric emptying is the most common complication of the surgical treatment
  • 36. Vagotomy • It performed under general anesthesia,incision is made in the patient’s abdomen and vagus nerve is located. Either the trunk or branches leading to stomach are cut. Then, the abdominal muscles are sewn back together and skin is closed with sutures.
  • 37. Types of vagotomy  Truncal or total abdominal vagotomy: • Total gastric or selective vagotomy • Proximal gastric or highly selective vagotomy
  • 39. Nursing management Nursing assessment : • Assess pain and methods used to relieve it; take a thorough history, including a 72-hour food intake history. • If patient has vomited, determine whether emesis is bright red or coffee ground in appearance. This helps identify source of the blood.
  • 40. • Ask patient about usual food habits, alcohol, smoking, medication use (NSAIDs), and level of tension or nervousness. • Ask how patient expresses anger (especially at work and with family), and determine whether patient is experiencing occupational stress or family problems. • Obtain a family history of ulcer disease. • Assess vital signs for indicators of anaemia (tachycardia, hypotension). • Assess for blood in the stools with an occult blood test. • Palpate abdomen for localized tenderness
  • 41. Nursing Diagnoses • Acute pain related to the effect of gastric acid secretion on damaged tissue • Anxiety related to coping with an acute disease • Imbalanced nutrition related to changes in diet • Deficient knowledge about preventing symptoms and managing the condition
  • 42. Complications • Hemorrhage: upper GI • Perforation • Penetration • Pyloric obstruction (gastric outlet obstruction)