This document summarizes a lecture on synthesizing science and spirituality. It discusses how scientific advances have created problems that science alone cannot solve. It then discusses how spirituality can be understood as the science of refining consciousness through practices like meditation, yoga, and contemplating divinity. The document calls for a synthesis of science and spirituality to limit unprincipled science and help spiritual practices evolve for the modern era. It provides examples of research institutions studying this synthesis through experiments on meditation's effects on physiology.