This document provides an introduction and definition of scientific literacy for the Programme for International Student Assessment (PISA). It discusses why scientific literacy is important at the national and international level to address challenges around resources, health, energy, and climate change. Scientific literacy is defined by PISA as the ability to engage in science-related issues as a citizen and demonstrated through three competencies: explaining scientific phenomena, evaluating and designing scientific inquiry, and interpreting scientific data and evidence. The document provides explanatory notes around PISA's focus on applying scientific knowledge to life situations and assessing the competencies based on the scientific concepts realistically expected of 15-year-olds.