This document discusses combining macroeconomic factors (F-atoms) and asset-specific risks (A-atoms) for portfolio construction and investment opportunities. It presents ANIMA SGR's quantitative research on developing global and local macro factor exposures (F-atoms) across different geographies and analyzing over 100 asset sensitivities. The goal is to navigate uncertain market conditions by taking robust exposure to macro themes and hedging against specific risks through a granular understanding of asset correlations to macro dynamics.