Power Automate Desktop allows users to build desktop automation flows using mouse and keyboard actions to streamline workflows across applications. It provides 400+ connectors to integrate with other systems. Desktop flows can automate tasks like running commands, obtaining text, interacting with email, executing SQL, and more. They are useful when APIs are not available or when dependent on local devices. The key components of Power Automate Desktop include the Console to manage flows and the Flow Designer development environment to create and debug flows using a toolbar, actions pane, workspace, and variables.