The paper presents a method for power system state estimation (SE) using a teaching-learning-based optimization (TLBO) algorithm, formulated as a constrained nonlinear programming problem. The proposed TLBO technique is demonstrated on the IEEE 14 bus test system, showing that it provides a global optimum solution and outperforms traditional methods like weighted least squares (WLS) and particle swarm optimization (PSO). The study emphasizes the efficacy of TLBO in addressing real-time control challenges within power systems.