This document provides guidance on preparing and prosecuting a patent application to obtain a patent that will withstand litigation. It discusses considerations prior to filing such as conducting a prior art search, carefully drafting claims to avoid obvious errors or unnecessary limitations, and ascertaining inventorship. During prosecution, it recommends fully complying with the duty of disclosure and using interviews and narrowing amendments strategically. Post-issuance, it suggests using certificates of correction, reissue applications, and reexamination where needed to strengthen the patent. The overall goal is to obtain a valid, enforceable patent by addressing weaknesses before they can be exploited in litigation.