The document outlines the key principles of effective instruction according to research. It discusses 10 principles informed by research on how the brain learns, best classroom practices, and teaching learning strategies to students. The principles include beginning lessons with review, presenting new material in small steps, checking for understanding, and providing scaffolds and independent practice. The document also examines how working memory and long-term memory function, noting instruction should aim to improve long-term memory storage. A quote emphasizes that nothing has truly been learned unless it changes long-term memory.