This document provides an overview of the CLYMA project, which aims to develop the freight transport connection between Lyon and Madrid along the Trans-European Transport Network (TEN-T) Mediterranean Corridor. The CLYMA project will focus on studies to optimize implementation of the TEN-T network and promote sustainable transport. It will also develop a management structure for the Lyon-Madrid intermodal transport corridor. The corridor passes through France and Spain, representing a significant portion of GDP and population in the EU. The project partners are transportation and logistics organizations from France and Spain that will work to identify bottlenecks and implement solutions to improve freight efficiency and connectivity between Lyon and Madrid.