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Percutaneous Transhepatic
Cholangiography
Presenter: Dr. Dheeraj Kumar
MRIT, Ph.D. (Radiology and Imaging)
Assistant Professor
Medical Radiology and Imaging Technology
School of Health Sciences, CSJM University, Kanpur
Contents
• Introduction to Percutaneous
Transhepatic Cholangiography
(PTC)
• Indications and Contraindications
• Procedure Overview
• Imaging Technique
• Interpretation of Results
• Advantages and Disadvantages
• Complications and Safety Measures
• Case Studies
• Conclusion
• Questions and Discussion
16/09/2023 PTC By- Dr. Dheeraj Kumar 2
Introduction to Percutaneous Transhepatic
Cholangiography (PTC)
• Definition: Percutaneous
Transhepatic Cholangiography
(PTC) is a radiographic procedure
used to visualize and assess the
biliary system, including the bile
ducts within the liver and those
leading to the small intestine.
16/09/2023 PTC By- Dr. Dheeraj Kumar 3
Anatomy
16/09/2023 PTC By- Dr. Dheeraj Kumar 4
Purpose
• PTC serves several essential purposes in radiography and healthcare:
• Diagnosis and assessment of biliary system disorders.
• Evaluation of bile duct blockages, strictures, or leaks.
• Preoperative planning for biliary surgery.
16/09/2023 PTC By- Dr. Dheeraj Kumar 5
History
• History of PTC reflects the ongoing commitment of radiologists and medical researchers
to refine and expand the capabilities of diagnostic radiology.
• From early experiments with contrast agents to the development of sophisticated
percutaneous techniques, PTC has made a lasting impact on the field of medical imaging
and the diagnosis and treatment of biliary system disorders.
• In recent years, the field of interventional radiology has continued to evolve with the
development of less invasive alternatives like magnetic resonance
cholangiopancreatography (MRCP) and endoscopic retrograde cholangiopancreatography
(ERCP).
16/09/2023 PTC By- Dr. Dheeraj Kumar 6
Pioneer Radiologists and Key Milestones
• Dr. Felix Berci: A pioneer in interventional radiology, Dr. Felix Berci
played a pivotal role in advancing PTC techniques in the 1960s and 1970s.
He introduced safer contrast agents and refined percutaneous puncture
methods.
• Dr. Jean-François Gigot: Dr. Gigot further advanced the field by
contributing to the understanding of PTC's diagnostic capabilities and its
role in guiding biliary surgery.
16/09/2023 PTC By- Dr. Dheeraj Kumar 7
Indications
• Suspected Biliary Obstruction: PTC is frequently performed when a patient
presents with symptoms such as jaundice, abdominal pain, or abnormal liver
function tests that may suggest biliary obstruction.
• Evaluation of Biliary Anatomy: It is utilized to obtain detailed information
about the biliary system's anatomy and any associated abnormalities.
• Preoperative Planning: Surgeons may request PTC images to plan surgical
interventions involving the biliary tract.
16/09/2023 PTC By- Dr. Dheeraj Kumar 8
Contraindications
• Allergy to Contrast Media: Individuals with known allergies to iodinated
contrast agents used in PTC should not undergo the procedure.
• Uncontrolled Bleeding Disorders: Patients with severe bleeding disorders
may not be suitable candidates for PTC due to the risk of hemorrhage.
• Severe Coagulopathy: Patients with coagulation disorders or anticoagulant
therapy may require careful consideration and potential adjustment of their
medications.
16/09/2023 PTC By- Dr. Dheeraj Kumar 9
Procedure Overview
• Patient Preparation:
• Consent and Explanation: Informed
consent is obtained from the patient,
and a detailed explanation of the
procedure is provided.
• Fasting Requirements: Patients are
typically instructed to fast for several
hours before the procedure to reduce
the risk of aspiration and ensure
optimal imaging conditions.
16/09/2023 PTC By- Dr. Dheeraj Kumar 10
Localization and Skin Marking
• Identifying the Puncture Site:
Imaging guidance, such as
ultrasound or fluoroscopy, is used
to identify the optimal puncture site
on the patient's abdomen.
• Skin Marking: The chosen puncture
site is marked on the patient's skin
for precise needle placement.
16/09/2023 PTC By- Dr. Dheeraj Kumar 11
Needle Puncture
• Accessing the Biliary System: A
thin, hollow needle is inserted
through the marked site, through
the liver tissue, and into the
biliary system under sterile
conditions and imaging guidance.
16/09/2023 PTC By- Dr. Dheeraj Kumar 12
Contrast Media Injection
• Visualization of the Biliary System:
A radiopaque contrast material is
injected through the needle into the
biliary system.
• Opacification of Ducts: The
contrast material opacifies the bile
ducts, allowing them to be
visualized on X-ray images.
16/09/2023 PTC By- Dr. Dheeraj Kumar 13
Imaging and Documentation
• X-ray or Fluoroscopy: Real-time X-ray images or fluoroscopic images
are captured to visualize the contrast's flow within the bile ducts.
• Static Images: Static images may be taken to document specific
findings or abnormalities.
16/09/2023 PTC By- Dr. Dheeraj Kumar 14
Catheter Placement
• Extended Contrast Injection
or Drainage: In some
cases, a catheter may be left
in place to facilitate
extended contrast injection,
drainage of bile, or
therapeutic interventions.
16/09/2023 PTC By- Dr. Dheeraj Kumar 15
Imaging Technique
• Radiographic Equipment:
• Fluoroscopy or X-ray Machine: PTC is
typically performed using fluoroscopy or
X-ray equipment to capture real-time and
static images.
• Image Intensifier: Fluoroscopy often
employs an image intensifier to enhance
image quality and reduce radiation
exposure.
16/09/2023 PTC By- Dr. Dheeraj Kumar 16
Contrast Media Characteristics
• Radiopaque Properties: The
contrast media used in PTC has
radiopaque properties, making
it visible on X-ray images.
• Opacification of Bile Ducts: It
selectively opacifies the bile
ducts, enhancing their visibility.
16/09/2023 PTC By- Dr. Dheeraj Kumar 17
Timing and Image Sequence
• Real-time Imaging: Real-time
fluoroscopy allows continuous
monitoring of the contrast flow during
injection.
• Static Images: Static X-ray images
are taken at specific points to
document findings and provide
detailed anatomical information.
16/09/2023 PTC By- Dr. Dheeraj Kumar 18
Interpretation of Results
Normal vs. Abnormal Findings:
• Normal Bile Duct Anatomy: In a normal PTC, the radiologist observes well-defined
bile ducts with a characteristic branching pattern.
• Identification of Abnormalities: PTC is invaluable for identifying various
abnormalities, including:
• Bile Duct Blockages: The procedure can pinpoint the location and extent of blockages caused
by factors like gallstones or tumors.
• Biliary Strictures: Narrowing or strictures in the bile ducts can be precisely identified.
• Biliary Leaks: PTC can detect leaks in the biliary system, often as a result of injury or surgery.
16/09/2023 PTC By- Dr. Dheeraj Kumar 19
Radiologist's Role
• Image Analysis: Radiologists play a central role in interpreting PTC
results. They analyze the images, identify abnormalities, and provide
detailed reports.
• Collaboration with Healthcare Team: Radiologists collaborate closely
with surgeons, gastroenterologists, and other healthcare professionals
to determine the best course of treatment based on the PTC findings.
16/09/2023 PTC By- Dr. Dheeraj Kumar 20
Advantages
• Direct Visualization: PTC provides direct visualization of the biliary
system, offering precise anatomical information.
• Diagnostic Precision: It is highly effective in diagnosing a wide range
of biliary conditions, guiding treatment decisions.
• Minimally Invasive: PTC is less invasive than surgical exploration and
can often replace more invasive procedures.
16/09/2023 PTC By- Dr. Dheeraj Kumar 21
Disadvantages
• Invasive Nature: PTC is an invasive procedure, involving percutaneous
access to the liver, which carries inherent risks.
• Risk of Complications: There is a risk of complications such as bleeding,
infection, or bile leakage, although these are relatively uncommon.
• Limited Therapeutic Role: While PTC is primarily diagnostic, it may also
guide some therapeutic interventions. However, it may not be suitable for
all cases or therapeutic purposes.
16/09/2023 PTC By- Dr. Dheeraj Kumar 22
Potential Complications
• Bleeding: PTC may lead to bleeding at the puncture site or within the
liver.
• Infection: Infection is a possible complication, although strict sterile
techniques are employed to minimize this risk.
• Perforation: Rarely, there may be unintended perforation of structures
within the liver or bile ducts.
16/09/2023 PTC By- Dr. Dheeraj Kumar 23
Safety Measures
• Sterile Technique: PTC is performed under strict sterile conditions to reduce
the risk of infection.
• Monitoring: Patients are closely monitored during and after the procedure to
detect and manage complications promptly.
• Preventive Measures: Care is taken to minimize bleeding risks, including
assessment of coagulation status, and correction of coagulopathies when
necessary.
16/09/2023 PTC By- Dr. Dheeraj Kumar 24
Case Studies
• Case 1: Biliary
Obstruction: Detail a
case where PTC
identified a biliary
obstruction, leading to a
diagnosis and treatment
plan.
16/09/2023 PTC By- Dr. Dheeraj Kumar 25
Case 2: Biliary Stricture
• Present a scenario
involving a biliary
stricture,
demonstrating how
PTC can precisely
locate and
characterize the
stricture.
16/09/2023 PTC By- Dr. Dheeraj Kumar 26
Case 3: Complications and Management
• Discuss a case
where complications
arose during PTC
and describe the
appropriate
management and
intervention.
16/09/2023 PTC By- Dr. Dheeraj Kumar 27
Conclusion
• The diagnostic significance of PTC in evaluating biliary system disorders.
• Indications and contraindications for the procedure.
• The procedure overview, including patient preparation, needle puncture, contrast media injection,
and imaging techniques.
• The role of radiologists in interpreting PTC results.
• Advantages, disadvantages, and safety considerations.
• Potential complications and safety measures.
• Real-world case studies showcasing the diagnostic and therapeutic utility of PTC.
16/09/2023 PTC By- Dr. Dheeraj Kumar 28
Questions and Discussion
Open the Floor for Questions? and Discussion @@
16/09/2023 PTC By- Dr. Dheeraj Kumar 29
Thank You
Express gratitude to the Students for their active participation, attention, and
contributions during the presentation.
16/09/2023 PTC By- Dr. Dheeraj Kumar 30
References
• "Radiologic Science for Technologists: Physics, Biology, and Protection"Authors: Stewart C.
Bushong, Publication Year: 2019, Publisher: Elsevier
• "Interventional Radiology Procedures in Biopsy and Drainage“, Authors: Ronald S. Arellano, Aldo
A. Maksoud,Publication Year: 2020, Publisher: Springer
• "Percutaneous Transhepatic Cholangiography: Techniques and Applications“,Authors: C. Christian,
H. Weismann, S. Dengler, et al.,Publication Year: 2021
• "Complications of Percutaneous Transhepatic Cholangiography in the Management of Postsurgical
Biliary Leaks and Strictures“, Authors: Arno NK Joseph, Peter Thuluvath, Publication Year: 2020
16/09/2023 PTC By- Dr. Dheeraj Kumar 31

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PTC.pptx

  • 1. Percutaneous Transhepatic Cholangiography Presenter: Dr. Dheeraj Kumar MRIT, Ph.D. (Radiology and Imaging) Assistant Professor Medical Radiology and Imaging Technology School of Health Sciences, CSJM University, Kanpur
  • 2. Contents • Introduction to Percutaneous Transhepatic Cholangiography (PTC) • Indications and Contraindications • Procedure Overview • Imaging Technique • Interpretation of Results • Advantages and Disadvantages • Complications and Safety Measures • Case Studies • Conclusion • Questions and Discussion 16/09/2023 PTC By- Dr. Dheeraj Kumar 2
  • 3. Introduction to Percutaneous Transhepatic Cholangiography (PTC) • Definition: Percutaneous Transhepatic Cholangiography (PTC) is a radiographic procedure used to visualize and assess the biliary system, including the bile ducts within the liver and those leading to the small intestine. 16/09/2023 PTC By- Dr. Dheeraj Kumar 3
  • 4. Anatomy 16/09/2023 PTC By- Dr. Dheeraj Kumar 4
  • 5. Purpose • PTC serves several essential purposes in radiography and healthcare: • Diagnosis and assessment of biliary system disorders. • Evaluation of bile duct blockages, strictures, or leaks. • Preoperative planning for biliary surgery. 16/09/2023 PTC By- Dr. Dheeraj Kumar 5
  • 6. History • History of PTC reflects the ongoing commitment of radiologists and medical researchers to refine and expand the capabilities of diagnostic radiology. • From early experiments with contrast agents to the development of sophisticated percutaneous techniques, PTC has made a lasting impact on the field of medical imaging and the diagnosis and treatment of biliary system disorders. • In recent years, the field of interventional radiology has continued to evolve with the development of less invasive alternatives like magnetic resonance cholangiopancreatography (MRCP) and endoscopic retrograde cholangiopancreatography (ERCP). 16/09/2023 PTC By- Dr. Dheeraj Kumar 6
  • 7. Pioneer Radiologists and Key Milestones • Dr. Felix Berci: A pioneer in interventional radiology, Dr. Felix Berci played a pivotal role in advancing PTC techniques in the 1960s and 1970s. He introduced safer contrast agents and refined percutaneous puncture methods. • Dr. Jean-François Gigot: Dr. Gigot further advanced the field by contributing to the understanding of PTC's diagnostic capabilities and its role in guiding biliary surgery. 16/09/2023 PTC By- Dr. Dheeraj Kumar 7
  • 8. Indications • Suspected Biliary Obstruction: PTC is frequently performed when a patient presents with symptoms such as jaundice, abdominal pain, or abnormal liver function tests that may suggest biliary obstruction. • Evaluation of Biliary Anatomy: It is utilized to obtain detailed information about the biliary system's anatomy and any associated abnormalities. • Preoperative Planning: Surgeons may request PTC images to plan surgical interventions involving the biliary tract. 16/09/2023 PTC By- Dr. Dheeraj Kumar 8
  • 9. Contraindications • Allergy to Contrast Media: Individuals with known allergies to iodinated contrast agents used in PTC should not undergo the procedure. • Uncontrolled Bleeding Disorders: Patients with severe bleeding disorders may not be suitable candidates for PTC due to the risk of hemorrhage. • Severe Coagulopathy: Patients with coagulation disorders or anticoagulant therapy may require careful consideration and potential adjustment of their medications. 16/09/2023 PTC By- Dr. Dheeraj Kumar 9
  • 10. Procedure Overview • Patient Preparation: • Consent and Explanation: Informed consent is obtained from the patient, and a detailed explanation of the procedure is provided. • Fasting Requirements: Patients are typically instructed to fast for several hours before the procedure to reduce the risk of aspiration and ensure optimal imaging conditions. 16/09/2023 PTC By- Dr. Dheeraj Kumar 10
  • 11. Localization and Skin Marking • Identifying the Puncture Site: Imaging guidance, such as ultrasound or fluoroscopy, is used to identify the optimal puncture site on the patient's abdomen. • Skin Marking: The chosen puncture site is marked on the patient's skin for precise needle placement. 16/09/2023 PTC By- Dr. Dheeraj Kumar 11
  • 12. Needle Puncture • Accessing the Biliary System: A thin, hollow needle is inserted through the marked site, through the liver tissue, and into the biliary system under sterile conditions and imaging guidance. 16/09/2023 PTC By- Dr. Dheeraj Kumar 12
  • 13. Contrast Media Injection • Visualization of the Biliary System: A radiopaque contrast material is injected through the needle into the biliary system. • Opacification of Ducts: The contrast material opacifies the bile ducts, allowing them to be visualized on X-ray images. 16/09/2023 PTC By- Dr. Dheeraj Kumar 13
  • 14. Imaging and Documentation • X-ray or Fluoroscopy: Real-time X-ray images or fluoroscopic images are captured to visualize the contrast's flow within the bile ducts. • Static Images: Static images may be taken to document specific findings or abnormalities. 16/09/2023 PTC By- Dr. Dheeraj Kumar 14
  • 15. Catheter Placement • Extended Contrast Injection or Drainage: In some cases, a catheter may be left in place to facilitate extended contrast injection, drainage of bile, or therapeutic interventions. 16/09/2023 PTC By- Dr. Dheeraj Kumar 15
  • 16. Imaging Technique • Radiographic Equipment: • Fluoroscopy or X-ray Machine: PTC is typically performed using fluoroscopy or X-ray equipment to capture real-time and static images. • Image Intensifier: Fluoroscopy often employs an image intensifier to enhance image quality and reduce radiation exposure. 16/09/2023 PTC By- Dr. Dheeraj Kumar 16
  • 17. Contrast Media Characteristics • Radiopaque Properties: The contrast media used in PTC has radiopaque properties, making it visible on X-ray images. • Opacification of Bile Ducts: It selectively opacifies the bile ducts, enhancing their visibility. 16/09/2023 PTC By- Dr. Dheeraj Kumar 17
  • 18. Timing and Image Sequence • Real-time Imaging: Real-time fluoroscopy allows continuous monitoring of the contrast flow during injection. • Static Images: Static X-ray images are taken at specific points to document findings and provide detailed anatomical information. 16/09/2023 PTC By- Dr. Dheeraj Kumar 18
  • 19. Interpretation of Results Normal vs. Abnormal Findings: • Normal Bile Duct Anatomy: In a normal PTC, the radiologist observes well-defined bile ducts with a characteristic branching pattern. • Identification of Abnormalities: PTC is invaluable for identifying various abnormalities, including: • Bile Duct Blockages: The procedure can pinpoint the location and extent of blockages caused by factors like gallstones or tumors. • Biliary Strictures: Narrowing or strictures in the bile ducts can be precisely identified. • Biliary Leaks: PTC can detect leaks in the biliary system, often as a result of injury or surgery. 16/09/2023 PTC By- Dr. Dheeraj Kumar 19
  • 20. Radiologist's Role • Image Analysis: Radiologists play a central role in interpreting PTC results. They analyze the images, identify abnormalities, and provide detailed reports. • Collaboration with Healthcare Team: Radiologists collaborate closely with surgeons, gastroenterologists, and other healthcare professionals to determine the best course of treatment based on the PTC findings. 16/09/2023 PTC By- Dr. Dheeraj Kumar 20
  • 21. Advantages • Direct Visualization: PTC provides direct visualization of the biliary system, offering precise anatomical information. • Diagnostic Precision: It is highly effective in diagnosing a wide range of biliary conditions, guiding treatment decisions. • Minimally Invasive: PTC is less invasive than surgical exploration and can often replace more invasive procedures. 16/09/2023 PTC By- Dr. Dheeraj Kumar 21
  • 22. Disadvantages • Invasive Nature: PTC is an invasive procedure, involving percutaneous access to the liver, which carries inherent risks. • Risk of Complications: There is a risk of complications such as bleeding, infection, or bile leakage, although these are relatively uncommon. • Limited Therapeutic Role: While PTC is primarily diagnostic, it may also guide some therapeutic interventions. However, it may not be suitable for all cases or therapeutic purposes. 16/09/2023 PTC By- Dr. Dheeraj Kumar 22
  • 23. Potential Complications • Bleeding: PTC may lead to bleeding at the puncture site or within the liver. • Infection: Infection is a possible complication, although strict sterile techniques are employed to minimize this risk. • Perforation: Rarely, there may be unintended perforation of structures within the liver or bile ducts. 16/09/2023 PTC By- Dr. Dheeraj Kumar 23
  • 24. Safety Measures • Sterile Technique: PTC is performed under strict sterile conditions to reduce the risk of infection. • Monitoring: Patients are closely monitored during and after the procedure to detect and manage complications promptly. • Preventive Measures: Care is taken to minimize bleeding risks, including assessment of coagulation status, and correction of coagulopathies when necessary. 16/09/2023 PTC By- Dr. Dheeraj Kumar 24
  • 25. Case Studies • Case 1: Biliary Obstruction: Detail a case where PTC identified a biliary obstruction, leading to a diagnosis and treatment plan. 16/09/2023 PTC By- Dr. Dheeraj Kumar 25
  • 26. Case 2: Biliary Stricture • Present a scenario involving a biliary stricture, demonstrating how PTC can precisely locate and characterize the stricture. 16/09/2023 PTC By- Dr. Dheeraj Kumar 26
  • 27. Case 3: Complications and Management • Discuss a case where complications arose during PTC and describe the appropriate management and intervention. 16/09/2023 PTC By- Dr. Dheeraj Kumar 27
  • 28. Conclusion • The diagnostic significance of PTC in evaluating biliary system disorders. • Indications and contraindications for the procedure. • The procedure overview, including patient preparation, needle puncture, contrast media injection, and imaging techniques. • The role of radiologists in interpreting PTC results. • Advantages, disadvantages, and safety considerations. • Potential complications and safety measures. • Real-world case studies showcasing the diagnostic and therapeutic utility of PTC. 16/09/2023 PTC By- Dr. Dheeraj Kumar 28
  • 29. Questions and Discussion Open the Floor for Questions? and Discussion @@ 16/09/2023 PTC By- Dr. Dheeraj Kumar 29
  • 30. Thank You Express gratitude to the Students for their active participation, attention, and contributions during the presentation. 16/09/2023 PTC By- Dr. Dheeraj Kumar 30
  • 31. References • "Radiologic Science for Technologists: Physics, Biology, and Protection"Authors: Stewart C. Bushong, Publication Year: 2019, Publisher: Elsevier • "Interventional Radiology Procedures in Biopsy and Drainage“, Authors: Ronald S. Arellano, Aldo A. Maksoud,Publication Year: 2020, Publisher: Springer • "Percutaneous Transhepatic Cholangiography: Techniques and Applications“,Authors: C. Christian, H. Weismann, S. Dengler, et al.,Publication Year: 2021 • "Complications of Percutaneous Transhepatic Cholangiography in the Management of Postsurgical Biliary Leaks and Strictures“, Authors: Arno NK Joseph, Peter Thuluvath, Publication Year: 2020 16/09/2023 PTC By- Dr. Dheeraj Kumar 31