PyMongo is a Python driver for working with MongoDB and allows developers to connect to MongoDB from Python, interface with MongoDB databases and collections, and perform common operations like inserting, finding, updating, and deleting documents. It maps common SQL concepts like databases, tables, and rows to MongoDB concepts like databases, collections, and BSON documents. The document provides examples of basic PyMongo operations for connecting to a MongoDB server, getting and working with databases and collections, and performing CRUD operations on documents.