Raman-ppt
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This document discusses Raman spectroscopy and its applications for medical diagnostics. It provides an overview of Raman spectroscopy principles and instrumentation. It then discusses various applications of Raman spectroscopy including in-vitro biofluid assays, in-vivo cancer detection using probes, and real-time Raman systems for skin cancer diagnosis. Raman spectroscopy is shown to be useful for applications ranging from laboratory testing to real-time clinical cancer detection.
Raman-ppt
- 1. Raman spectroscopy for medical diagnosticsRaman spectroscopy for medical diagnostics From in-vitro biofluid assays to in-vivo cancerFrom in-vitro biofluid assays to in-vivo cancer detectiondetection 11
- 2. Raman SpectroscopyRaman Spectroscopy PrinciplePrinciple InstrumentInstrument ApplicationsApplications First Raman SpectraFirst Raman Spectra 22 19301930 – C.V. Raman wins Nobel Prize in Physics– C.V. Raman wins Nobel Prize in Physics http://www.springerlink.com/content/u4d7aexmjm8pa1fv/fulltext.pdfhttp://www.springerlink.com/content/u4d7aexmjm8pa1fv/fulltext.pdf
- 3. Raman principleRaman principle Infrared (absorption) Raman (scattering) v” = 0 v” = 1 virtual state Excitation Scattered 33 www.andor.comwww.andor.com
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- 8. 88 Diagram of the SERS-based sandwich immunoassay. Antibody-conjugated SERSDiagram of the SERS-based sandwich immunoassay. Antibody-conjugated SERS tags serve as labels for the biological analyte and are captured bytags serve as labels for the biological analyte and are captured by superparamagnetic beads which are also functionalized with antibodies specificsuperparamagnetic beads which are also functionalized with antibodies specific to the analyte. A Raman laser strikes the SERS tags, generating a uniqueto the analyte. A Raman laser strikes the SERS tags, generating a unique spectrum that easily identifies analytes.spectrum that easily identifies analytes. Identifying biological agents with surface-enhanced Raman scattering. 18 April 2011, SPIEIdentifying biological agents with surface-enhanced Raman scattering. 18 April 2011, SPIE Newsroom.DOLNewsroom.DOL
- 9. In vitro Raman spectroscopyIn vitro Raman spectroscopy 99
- 10. In vivo Raman spectroscopyIn vivo Raman spectroscopy 1010
- 11. 1111 The handheld contact fiber optic probe for Raman spectroscopy.The handheld contact fiber optic probe for Raman spectroscopy. Intraoperative brain cancer detection with Raman spectroscopy in humans. ScienceIntraoperative brain cancer detection with Raman spectroscopy in humans. Science Translational Medicine 11 Feb 2015Translational Medicine 11 Feb 2015
- 12. Real-time Raman systemReal-time Raman system 1212 Schematic configuration of the real-time Raman system for skin cancerSchematic configuration of the real-time Raman system for skin cancer diagnosis.diagnosis. Real-time Raman Spectroscopy for In Vivo Skin Cancer Diagnosis.Real-time Raman Spectroscopy for In Vivo Skin Cancer Diagnosis. 2012 May 15;72(10):2491-5002012 May 15;72(10):2491-500