Rapid sequence intubation involves several key steps:
1. Preoxygenation of the patient with 100% oxygen for 3 minutes to establish an oxygen reserve before intubation.
2. Administration of sedatives and neuromuscular blocking agents (NMBAs) to gain control of the airway without risk of aspiration.
3. Placement of the endotracheal tube once paralysis is achieved, confirmed by lack of muscle tone and ability to ventilate if oxygen saturation drops below 90%.
4. Postintubation management including chest x-ray, use of long-acting NMBAs, and sedation to facilitate mechanical ventilation.