This document analyzes the seismic performance of multi-story buildings with flat slab and grid slab structures in seismic zones III and V. Finite element software ETABS is used to model T-shaped and L-shaped buildings with 15 stories and both slab systems. Response spectrum analysis is conducted to determine parameters like base shear and storey shear. The results show that grid slab structures experience higher base shear values than equivalent flat slab buildings in both zones. In conclusion, grid slab structures perform poorer seismically compared to flat slab structures for the building geometries and conditions analyzed.