This paper compares the effectiveness of sequential versus random neighborhood selection methods in the Variable Neighborhood Descent (VND) algorithm for solving the Capacitated Vehicle Routing Problem (CVRP). Experimental results indicate that random selection outperforms sequential selection in optimal route length for 10 out of 13 datasets, although it requires more iterations to converge. The study highlights the importance of neighborhood operator selection in enhancing the performance of VND in solving combinatorial optimization problems.