The document discusses making function calls in R. It explains that a function call requires a function name and arguments within parentheses. Arguments can be named or unnamed. When arguments are named, their position does not matter, but when unnamed, their values must be provided in the correct order to match the function's expected arguments. The document provides examples of making function calls using the mean() function to illustrate named versus unnamed arguments and the importance of argument position when unnamed. It also discusses other function components like the function name, default argument values, and anonymous functions.