Mechanical ventilation involves using a machine to assist or replace spontaneous breathing. It is commonly used in ICUs for patients with respiratory failure or decreased lung function. The document discusses the history of mechanical ventilation, its indications, types including positive and negative pressure modes, settings, complications, and nursing management of ventilated patients. The main types of positive pressure ventilation are controlled mandatory ventilation (CMV), assisted-control ventilation (ACV), and synchronized intermittent mandatory ventilation (SIMV). Settings include respiratory rate, tidal volume, oxygen concentration, and PEEP. Complications can include pneumonia, hypotension, and increased intracranial pressure.