SQL Server is a relational database management system developed by Microsoft that supports the SQL language. It has various editions like Enterprise, Standard, and Web. SQL Server allows running multiple instances of the same version on a single machine for benefits like installation of different versions, maintenance of environments, and reducing temporary problems. Key features include creating, altering, and dropping databases and tables. Data can be manipulated using insert, update, and delete commands. Primary keys, foreign keys, unique constraints, and indexes can be defined to enforce data integrity and improve query performance.