Synthesis report template 3 asperin
- 1. 1 ORGANIC CHEMISTRY LABORATORY REPORT LEARNER NAME: Hazrat Billal Group AN, AM , PM Date 19-03-18 Experiment Number e.g 030 Title the preparation of Aspirin Criteria covered by this practical Unit 28 P6, M4, D4 Reaction (Use Accelrys Draw or Chem Draw) Materials Reactants RMM (g/mol) Mass (g) Moles COSHH Salicylic Acid (- 2) Hydrozybenzoic acid 138 2.00 0.014 R22-41 S26-39 Ethanoic acid anhydride 102 5.00 0.048 R10-34 S26-45 Phosphoric acid 98 2.00 0.020 R34 S26-45
- 2. 2 ORGANIC CHEMISTRY LABORATORY REPORT Method Salicylic acids (2g) was added in a pear shape flask together with ethanoic anhydride (5cm3) and 5 drop of phosphoric acids were also added. Then the mixture was heated for 10 minutes then the ice was added and the mixture putted to water white solid was collected. The flask was placed in cold water bath to cool down and was left therefore, the crystal was able to form the crude crystals was poured through a Buckner funnel so it can be filtered, the dry aspirin was putted with (20ml) of boiling ethanol to dissolve the crystals 10ml of ethanol was added then the filtration process was done the precipitate was filtered to remove the impurities. Then it was putted into a beaker and a half of the volume of the filtered distilled water was added. It was then measured and recorded and left to be cooled down. Results One mole of SA gives 1 mole of ASA 2/138 moles of SA gives 2/138 moles Therefore, theoretical yield of ASA= 0.014 moles Mass/ RMM= Moles Mass = 0.0014×180= 2.6 Percentage yield A/T×100 2.14/2.16×100= 82% Percentage yield = 82 %