Tailored communication aims to create targeted health messages for individuals based on their unique characteristics. It seeks to increase personal relevance and involvement to better influence behavior change. Research shows tailored interventions can be effective by providing customized messaging that increases relevance, though the impact of message framing on behavior is complex. While gains frames may work better for preventive behaviors like dental hygiene, the effect of framing depends on the behavior and individual motivations being addressed. Ongoing research is needed to refine practical guidelines for developing optimally persuasive health messages.