Trial x allscripts_submission
- 1. Applied Informatics Inc Matching Patients to Clinical trials using EHR Data Team Members: Yaseen, Aamir, Shahid, Sharib and Chintan Copyright © 2011 Allscripts Healthcare Solutions, Inc. 1
- 2. Solution Overview Ø The TrialX Allscript EHR application is designed for two important use cases • Automatically match a given patient to a database of ongoing clinical trials, so as to facilitate recruitment at the point of care during an office visit • Enable the provider to run a cross patient query on the EHR to find patients that may be eligible for a specific clinical trial A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 2
- 3. Problem – Finding Patients for Clinical trials Ø Clinical Trials are a critical step in the drug development pipeline Ø Approximately 50,000 trials are conducted annually Ø Finding eligible participants is a major hurdle in timely completion of clinical trials Ø 80% of clinical trials get delayed Ø Each days delay on average is $1-3million in lost revenue for pharmaceutical companies A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 4. Problem – Lack of Information Ø Most physicians (68%) are not aware of which clinical trials are suitable for their patients and are unable to provide this information during a clinic visit Ø EHRs have the potential to help identify eligible patients and to alert physicians if patients match a trial Ø However, few EHRs have any, easy-to-use application to • Find which trials maybe suitable for a given patient • Refer the patient to the matching trial sites • Or queries to find a cohort of patients that may qualify for a given study and inform them about it A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 5. Use Case 1: Matching Patients to Clinical Trials Ø The application automatically matches a given patient record to clinical trials Ø Allows the provider to refer the patient to the matching site in one click via email Ø Saves a note in the patient’s EHR for future reference A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 6. Use Case 2: Find Patients for a Given Trial Ø Allows providers to run query to find suitable matches for a given trial • Age • Gender • Location • Condition • Medication Ø Send a voice message to all matching patients informing them of the study A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 7. Matching Patient to a Trial Step 2: The application queries the AllScripts EHR to Step 1: The Provider accesses the application from access patient information within the Allscripts EEHR, say during a patient encounter A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 8. Matching Patient to a Trial Step 3: list of matching trials are displayed, sorted by Step 4: Patient is referred by provider to research nearest distance to patient zip code. Additional filters site by email and the patients complete CDA is like Phase are provided to narrow down results. attached for the investigators to review “Refer Now” button is provided A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 9. Use Case 2: Find Patients Matching a Trial Step 1. Provider has a Breast Cancer trial. He can Step 2: The application queries the AllScripts EEHR, enter the criteria to find patients with that Condition using GetPatientsbyICD9 code to retrieve patient entered CDA and then match against other criteria A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 10. Find Patients Matching a Trial Step 4: The System Dials all the matching Step 3: Provider can then enter a message patients, pulling their phone number from the that will be broadcast to the patient as an EHR and the message entered by the provider is automated Phone Call spoken out to the patient. Step 5: Provider can see number of calls completed and responses entered by the patients A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 11. Technical Details Ø The TrialX App is integrated with the AllScripts EHR using the API and can run across any browser Ø The app uses several API calls to both read and push data to the EHR Ø App works for a specific patient and also performs cross patient queries Ø Integrated with a cloud-service to make automated calls Ø Built as a Django/Python application that works across browsers Ø Runs as a Windows 8 Application as well A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 12. Development Details Ø TrialX is currently live across 5 major academic medical centers and used by over 1.5 million patient visitors on trialx.com every month Ø Allscripts API calls used Ø TrialX uses EEHR/Unity API to fetch provider and patient information. Ø API Calls Used Ø GetPatientFull Ø GetPatientsByICD Ø GetPatientSections Ø SearchDiagnosesCodes A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 12
- 13. App Info Ø http://ehr2trials.trialx.com:8001/erecord/?patientID=90 Ø Video link Ø Video shows the doctor accessing the application to find trials matching a given patient and then referring the patient to the site. It also shows the provider running a query on their database to find patients matching a study criteria and then sending them an automated voice message A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
- 14. Next Steps Ø NewYork-Presbyterian Hospital, one of our current TrialX clients, would be an important site to pilot the application as the hospital uses Allscripts EHR Ø Perform full-clinical record semantic matching using laboratory values, procedures to find more specific matches A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.