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Understanding the Mechanism
of Action of the Mini-Gastric
Bypass
The MGB is NOT
the
“Single Anastomosis Bypass”
• The crital component of the MGB
IS NOT the single anastomosis
• Error in Naming Demonstrates
• Misunderstanding the MGB
MGB Criticisms by
year 2000 American Surgeons
• Dr Rutledge did not take out the
gallbladder
• MGB was not retro colic/ retro gastric
• The MGB = Old Mason GBP and
All would suffer Bile Reflux Esophagitis
• Billroth II causes cancer
• The Pouch and the Gastro-j were too big
and the patients would not lose weight
• DrR used Email!, DrR had a website
Almost 20 Years Later
Surgeons Still Misunderstand
the MGB
• The MGB is NOT a
“RNY with One Less Anastomosis”
• You Cannot Understand the Anatomy of
the MGB (Surgical Technique)
• Unless you understand the MGB
Mechanism of Action
The Name
• Misunderstanding:
MGB is Nothing more than RNY with
One Less Anastomosis
• **Wrong**
• This erroneous thinking lead to the
renaming of the MGB to
• “Single Anastomosis Bypass”
• Lets Explain the misunderstanding
• MGB - RNY are not the same
?? MGB Best Bariatric Surgery ??
Sample Recent Study
Obes Surg. 2017 Sep;27(9):2479-2487
MGB vs. Sleeve Gastrectomy for Morbid Obesity: Systematic
Review and Meta-analysis Magouliotis DE
Seventeen studies 6761 patients
This study reveals:
“increased weight loss, remission of comorbidities, shorter
mean hospital stay, and lower mortality in the MGB group”
“Sleeve Higher Rate GERD”
Understanding the Obvious
If Not an MGB Expert, Do Not do the MGB!
• First: If you do not understand an operation (MGB)
• Do Not Use the Operation!!
• In Short: This Presentation in Summary:
1. Widespread and Persistent Misunderstanding of MGB
2. Often Leading to Complications and Even Death
3. Needed:
* Standardization of MGB,
** Education and
*** Recognition of Knowledgeable and Skilled Surgeons
Needed: Standardization of MGB and
Recognition of Surgeons Knowledgeable
and Skilled in its use
* Standardize, ** Educate, *** Recognize
The Best in MGB
Please Join The Board of Governors!
MGBReviewCorp.com
Invitation to Join the Board of Governors of the MGB
Review Corp
I invite you to join the Board of Governors of the MGB Review Corporation
For Excellence in the MGB!
1. Complete the MGB Review Corporation Information Form
https://www.surveymonkey.com/r/MRCReviewCorp
2.Join the Facebook Page and Group: MGBReviewCorp
https://www.Facebook.com/MGBReviewCorp/
https://www.Facebook.com/groups/MGBReviewCorp
Please join us to initiate your participation in the group process
Email, Call or Message for more information or to give advice and your opinions:
​Email: DrR@clos.net, Facebook: DrRRutledge
Facebook Messenger: @DrRRutledge,
Phone: 702-483-7133 or 702-714-0011 or What's App: Dr Rutledge
Confusion By Surgeons Who Do Not
Understand the MGB
How Often
Have Surgeons
And
Continue to Be Wrong
About the Mini-Gastric Bypass?
Confusion By Surgeons Who Do Not
Understand the MGB
Some Examples of MGB Confusion
1. The Pouch is Too Big & Pts Will Not Loose Weight
2. Short Gastric Pouch (MGB = Old Mason Loop)
3. Dissection EG Junction and crural Repair
4. MGB with a “Ring”
5. Irrational Fear of Bile Reflux
6. Confused About Risk Gastric Cancer
7. Fear of Malnutrition
8. Management of MGB Complications
And More...
MGB Anatomy =
Mechanism of Action
1. Non-Obstructive Restriction
2. Fatty Food Intolerance =>
Change preferences in Food
3. Fatty Food Malabsorption to
High Fat Meal
4. Post Gastrectomy Syndrome
Understanding
Good Dumping/Bad Dumping
5. Post-Gastrectomy Syndrome Diet
Bariatric Surgeons Forget
History of GI Surgery
What have we learned from
100 years of GI Surgery?
MGB = Post Gastrectomy
=> (Sweets + Fatty Food) Intolerance
• It’s Just General Surgery!
• For over 75 years
• Sweet + Fatty food intolerance common
“Post Gastrectomy Syndrome”
• More common & Greater degree with
• Billroth II >> Billroth I
•
EVERSON TC. Experimental comparison of protein and fat assimilation after Billroth II, Billroth I,
and segmental types of subtotal gastrectomy. Surgery. 1954 Sep;36(3):525-37
• MACLEAN LD, PERRY JF, KELLY WD, MOSSER DG, MANNICK A, WANGENSTEEN OH.
Nutrition following subtotal gastrectomy of four types (Billroth I and II, segmental, and tubular
resections). Surgery. 1954 May;35(5):705-18
• WOLLAEGER EE, WAUGH JM, POWER MH. Fat-assimilating capacity of the gastrointestinal
tract after partial gastrectomy with gastroduodenostomy (Billroth I anastomosis).
Gastroenterology. 1963 Jan;44:25-32
• …
100 Years of GI Surgery:
Sweets + Fatty Food Intolerance Gastric Operations:
• What do we know:
Sweets/Fatty Food Intolerance
• “Rare after gastro-jejunostomy or
vagotomy alone.
• “Rare after RNY, Billroth I
• “Especially Common after
Polya type Billroth II
• (**Butler, 1961**)
Polya Type Gastro-Jejunostomy
(HELLO; MGB Not RNY)
NOTE:
Large
Wide Open
Gastro-
jejunostomy
Bariatric Surgical Procedures
Problems
– Vertical Banded Gastroplasty: (Abandoned)
Failed Weight Regain
– Lap Band: (Abandoned)
Failed Weight Regain
– Sleeve: (Worrisome New Data)
Failed Weight Regain & GE Reflux, Barretts
– Roux-en-Y: (Highest Risk Complications)
Weight regain,
– BPD / Duodenal Switch / SADI: Malnutrition,
Deficiencies, Diarrhea, Foul Smelling Gas
Understanding
1. Dumping Syndrome &
2. Post Gastrectomy
Syndrome
3. Mini-Gastric Bypass
Good Dumping / Bad Dumping
Aversive Conditioning
OBSTRUCTIVE Restrictive Procedures:
Mechanism of Action & Failure
• Mechanism of Action & Failure
• Restriction / OBSTRUCTION
• Weight Loss induced by
High Grade Narrowing (Stricture) =
Obstruction of Normal Healthy Food
(i.e. Broccoli, Sandwich, Apple etc.) => Vomiting
• Induces “Pathologic Eating” (i.e. Coca Cola,
Soda, “Soft Calories”, Candy, Ice Cream, etc.)
=> Failure: Weight Regain
Selecting an Operative Procedure
Safety and Effectiveness
Personal Experience, Animal Models, Expert Judgment,
Published Data and Controlled Prospective Randomized
Trials all show:
MGB is More Effective than Sleeve  RNY
MGB is Safer than Sleeve  RNY
BUT ONLY IN
WELL TRAINED HANDS!
Why the Band/Sleeve/RNY
Fail
All OBSTRUCTIVE Restrictive Procedures
Stricture: Block “Healthy Foods”
Induce Intake of Sweets,
"Liquid Calories" &
“Junk Food”
Pathologic Dietary Choices
Calories:
Ice Cream 200g/540 cal,
2 Milky-way Bars, 1,000 cal
2 L Bottle Coke 830 cal
Total: 2,370 cal
Band/Sleeve/RNY
Create Sweet/Junk Food Eaters
• All OBSTRUCTIVE Restrictive Procedures
(Including RNY) MAKE SWEET EATERS:
• Mechanical Block of
Normal Healthy Foods
• Early Weight Loss: Honeymoon +/- 2 years
• Then Failure Weight Regain
• Why is there a growing chorus in favor of
“Banding” the RNY?
Band, Sleeve, RNY
Block Normal Healthy Foods
• Weight Loss =>
• Increased Hunger
• Decreased Satiety
• Healthy Foods Blocked
• Drive to Eat Increased
• What Happens?
Early Dumping syndrome
• Onset in 15 to 30 min
• Rapid shift extracellular fluid into SB
(rapid passage and hyperosmolarity)
>> acute distension >> Autonomic Sx
• Most Common *** B II reconstruction ***
• GI Sxs : N/V, Fullness, Cramping & Diarrhea
• CVS : palpitation, tachycardia, diaphoresis
Late Dumping syndrome
•Carbohydrate load in diet to the stomach
•>> rapid gastric emptying pass to SB
•>> hyperglycemia
•>> insulin over shoot
•>> cathecholamines stimulation
•Sx: Mild to severe
weakness, sweating, and dizziness
Dumping and Effectiveness in Sleeve
• Obes Surg. 2015 The Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery
on Dietary Intake, Food Preferences, and Gastrointestinal Symptoms, El Labban
• Gastroenterol Res Pract. 2016, Risk of Dumping Syndrome after Sleeve Gastrectomy and
Roux-en-Y Gastric Bypass Ramadan M. RYGB, especially with larger gastrojejunal
anastomosis, are more prone to developing DS following surgery than patients
undergoing LSG
• Obes Surg. 2012 Dumping symptoms and incidence of hypoglycaemia after provocation
test at 6 and 12 months after laparoscopic sleeve gastrectomy. Papamargaritis D
“Symptoms suggestive of dumping syndrome were recorded in 40 % of patients at 6
months and in 33 % at 12 months postoperatively.”
• Obes Surg. 2012 Symptoms suggestive of dumping syndrome after provocation in
patients after laparoscopic sleeve gastrectomy Tzovaras “SG 9 patients (29%)
experienced definite dumping and other 5 patients (16%) symptoms suggestive of
dumping syndrome”
What Make'e
The MGB
So Good?
Hint:
It's the Surgical Technique
It's the Billroth II
BP Limb
Not Lap Band, Sleeve, RNY
Mini-Gastric Bypass Decreases Hunger
Dr Rutledge's Survey 2,783 Pts
What About the MGB
Re: Restriction withouth Obstruction
Secondary to
Post Gastrectomy Syndrome
Mini-Gastric Bypass (MGB):
Surgical Rx of Obesity / Diabetes
1. NON-Obstructive Restriction
2. Fatty Food Intolerance w
3. Minimal Malabsorption
4. Decreased Hunger
Enforced Healthy Mediterranean Diet
Post Gastrectomy Syndrome
•Rapid Gastric Emptying
•The Bulk Food component draws water into the
intestinal lumen causing sudden fluid shifts in
the early dumping whereas
•Late dumping is caused by a reactive
hypoglycemia.
MGB: BPLimb + Post
Gastrectomy Syndrome
• Dog Study 1950,
Rapid Gastric Emptying into Small Bowel
• Antrectomy and Billroth II
Bilio-Pancreatic Limb Bypass
Bowel Bypass 5% No effect
Bowel Bypass 15% No Effect
Bowel Bypass 30% ++Fatty food
intolerance, +Fat Malabsorption
• ~30% Bypass = MGB
Post Gastrectomy Syndrome (PGS)
MGB Diet PGS Diet
• 6 small feeds
• Avoid Sweets, Fats
• Avoid High Fat, Fried
Food
• More Fresh Fruit Vegs
• More Dairy (xLactose)
• Minimal Liquids
• ...
• 6 small feeds
• Avoid Sweets, Fats
• Avoid High Fat, Fried
Food
• More Fresh Fruit Vegs
• More Dairy (xLactose)
• Minimal Liquids
• ...

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Understanding the Mechanism of Action of the Mini-Gastric Bypass

  • 1. Understanding the Mechanism of Action of the Mini-Gastric Bypass
  • 2. The MGB is NOT the “Single Anastomosis Bypass” • The crital component of the MGB IS NOT the single anastomosis • Error in Naming Demonstrates • Misunderstanding the MGB
  • 3. MGB Criticisms by year 2000 American Surgeons • Dr Rutledge did not take out the gallbladder • MGB was not retro colic/ retro gastric • The MGB = Old Mason GBP and All would suffer Bile Reflux Esophagitis • Billroth II causes cancer • The Pouch and the Gastro-j were too big and the patients would not lose weight • DrR used Email!, DrR had a website
  • 4. Almost 20 Years Later Surgeons Still Misunderstand the MGB • The MGB is NOT a “RNY with One Less Anastomosis” • You Cannot Understand the Anatomy of the MGB (Surgical Technique) • Unless you understand the MGB Mechanism of Action
  • 5. The Name • Misunderstanding: MGB is Nothing more than RNY with One Less Anastomosis • **Wrong** • This erroneous thinking lead to the renaming of the MGB to • “Single Anastomosis Bypass” • Lets Explain the misunderstanding • MGB - RNY are not the same
  • 6. ?? MGB Best Bariatric Surgery ?? Sample Recent Study Obes Surg. 2017 Sep;27(9):2479-2487 MGB vs. Sleeve Gastrectomy for Morbid Obesity: Systematic Review and Meta-analysis Magouliotis DE Seventeen studies 6761 patients This study reveals: “increased weight loss, remission of comorbidities, shorter mean hospital stay, and lower mortality in the MGB group” “Sleeve Higher Rate GERD”
  • 7. Understanding the Obvious If Not an MGB Expert, Do Not do the MGB! • First: If you do not understand an operation (MGB) • Do Not Use the Operation!! • In Short: This Presentation in Summary: 1. Widespread and Persistent Misunderstanding of MGB 2. Often Leading to Complications and Even Death 3. Needed: * Standardization of MGB, ** Education and *** Recognition of Knowledgeable and Skilled Surgeons
  • 8. Needed: Standardization of MGB and Recognition of Surgeons Knowledgeable and Skilled in its use * Standardize, ** Educate, *** Recognize The Best in MGB Please Join The Board of Governors! MGBReviewCorp.com
  • 9. Invitation to Join the Board of Governors of the MGB Review Corp I invite you to join the Board of Governors of the MGB Review Corporation For Excellence in the MGB! 1. Complete the MGB Review Corporation Information Form https://www.surveymonkey.com/r/MRCReviewCorp 2.Join the Facebook Page and Group: MGBReviewCorp https://www.Facebook.com/MGBReviewCorp/ https://www.Facebook.com/groups/MGBReviewCorp Please join us to initiate your participation in the group process Email, Call or Message for more information or to give advice and your opinions: ​Email: DrR@clos.net, Facebook: DrRRutledge Facebook Messenger: @DrRRutledge, Phone: 702-483-7133 or 702-714-0011 or What's App: Dr Rutledge
  • 10. Confusion By Surgeons Who Do Not Understand the MGB How Often Have Surgeons And Continue to Be Wrong About the Mini-Gastric Bypass?
  • 11. Confusion By Surgeons Who Do Not Understand the MGB Some Examples of MGB Confusion 1. The Pouch is Too Big & Pts Will Not Loose Weight 2. Short Gastric Pouch (MGB = Old Mason Loop) 3. Dissection EG Junction and crural Repair 4. MGB with a “Ring” 5. Irrational Fear of Bile Reflux 6. Confused About Risk Gastric Cancer 7. Fear of Malnutrition 8. Management of MGB Complications And More...
  • 12. MGB Anatomy = Mechanism of Action 1. Non-Obstructive Restriction 2. Fatty Food Intolerance => Change preferences in Food 3. Fatty Food Malabsorption to High Fat Meal 4. Post Gastrectomy Syndrome Understanding Good Dumping/Bad Dumping 5. Post-Gastrectomy Syndrome Diet
  • 13. Bariatric Surgeons Forget History of GI Surgery What have we learned from 100 years of GI Surgery?
  • 14. MGB = Post Gastrectomy => (Sweets + Fatty Food) Intolerance • It’s Just General Surgery! • For over 75 years • Sweet + Fatty food intolerance common “Post Gastrectomy Syndrome” • More common & Greater degree with • Billroth II >> Billroth I • EVERSON TC. Experimental comparison of protein and fat assimilation after Billroth II, Billroth I, and segmental types of subtotal gastrectomy. Surgery. 1954 Sep;36(3):525-37 • MACLEAN LD, PERRY JF, KELLY WD, MOSSER DG, MANNICK A, WANGENSTEEN OH. Nutrition following subtotal gastrectomy of four types (Billroth I and II, segmental, and tubular resections). Surgery. 1954 May;35(5):705-18 • WOLLAEGER EE, WAUGH JM, POWER MH. Fat-assimilating capacity of the gastrointestinal tract after partial gastrectomy with gastroduodenostomy (Billroth I anastomosis). Gastroenterology. 1963 Jan;44:25-32 • …
  • 15. 100 Years of GI Surgery: Sweets + Fatty Food Intolerance Gastric Operations: • What do we know: Sweets/Fatty Food Intolerance • “Rare after gastro-jejunostomy or vagotomy alone. • “Rare after RNY, Billroth I • “Especially Common after Polya type Billroth II • (**Butler, 1961**)
  • 16. Polya Type Gastro-Jejunostomy (HELLO; MGB Not RNY) NOTE: Large Wide Open Gastro- jejunostomy
  • 17. Bariatric Surgical Procedures Problems – Vertical Banded Gastroplasty: (Abandoned) Failed Weight Regain – Lap Band: (Abandoned) Failed Weight Regain – Sleeve: (Worrisome New Data) Failed Weight Regain & GE Reflux, Barretts – Roux-en-Y: (Highest Risk Complications) Weight regain, – BPD / Duodenal Switch / SADI: Malnutrition, Deficiencies, Diarrhea, Foul Smelling Gas
  • 18. Understanding 1. Dumping Syndrome & 2. Post Gastrectomy Syndrome 3. Mini-Gastric Bypass Good Dumping / Bad Dumping Aversive Conditioning
  • 19. OBSTRUCTIVE Restrictive Procedures: Mechanism of Action & Failure • Mechanism of Action & Failure • Restriction / OBSTRUCTION • Weight Loss induced by High Grade Narrowing (Stricture) = Obstruction of Normal Healthy Food (i.e. Broccoli, Sandwich, Apple etc.) => Vomiting • Induces “Pathologic Eating” (i.e. Coca Cola, Soda, “Soft Calories”, Candy, Ice Cream, etc.) => Failure: Weight Regain
  • 20. Selecting an Operative Procedure Safety and Effectiveness Personal Experience, Animal Models, Expert Judgment, Published Data and Controlled Prospective Randomized Trials all show: MGB is More Effective than Sleeve RNY MGB is Safer than Sleeve RNY BUT ONLY IN WELL TRAINED HANDS!
  • 21. Why the Band/Sleeve/RNY Fail All OBSTRUCTIVE Restrictive Procedures Stricture: Block “Healthy Foods” Induce Intake of Sweets, "Liquid Calories" & “Junk Food”
  • 22. Pathologic Dietary Choices Calories: Ice Cream 200g/540 cal, 2 Milky-way Bars, 1,000 cal 2 L Bottle Coke 830 cal Total: 2,370 cal
  • 23. Band/Sleeve/RNY Create Sweet/Junk Food Eaters • All OBSTRUCTIVE Restrictive Procedures (Including RNY) MAKE SWEET EATERS: • Mechanical Block of Normal Healthy Foods • Early Weight Loss: Honeymoon +/- 2 years • Then Failure Weight Regain • Why is there a growing chorus in favor of “Banding” the RNY?
  • 24. Band, Sleeve, RNY Block Normal Healthy Foods • Weight Loss => • Increased Hunger • Decreased Satiety • Healthy Foods Blocked • Drive to Eat Increased • What Happens?
  • 25. Early Dumping syndrome • Onset in 15 to 30 min • Rapid shift extracellular fluid into SB (rapid passage and hyperosmolarity) >> acute distension >> Autonomic Sx • Most Common *** B II reconstruction *** • GI Sxs : N/V, Fullness, Cramping & Diarrhea • CVS : palpitation, tachycardia, diaphoresis
  • 26. Late Dumping syndrome •Carbohydrate load in diet to the stomach •>> rapid gastric emptying pass to SB •>> hyperglycemia •>> insulin over shoot •>> cathecholamines stimulation •Sx: Mild to severe weakness, sweating, and dizziness
  • 27. Dumping and Effectiveness in Sleeve • Obes Surg. 2015 The Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery on Dietary Intake, Food Preferences, and Gastrointestinal Symptoms, El Labban • Gastroenterol Res Pract. 2016, Risk of Dumping Syndrome after Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Ramadan M. RYGB, especially with larger gastrojejunal anastomosis, are more prone to developing DS following surgery than patients undergoing LSG • Obes Surg. 2012 Dumping symptoms and incidence of hypoglycaemia after provocation test at 6 and 12 months after laparoscopic sleeve gastrectomy. Papamargaritis D “Symptoms suggestive of dumping syndrome were recorded in 40 % of patients at 6 months and in 33 % at 12 months postoperatively.” • Obes Surg. 2012 Symptoms suggestive of dumping syndrome after provocation in patients after laparoscopic sleeve gastrectomy Tzovaras “SG 9 patients (29%) experienced definite dumping and other 5 patients (16%) symptoms suggestive of dumping syndrome”
  • 28. What Make'e The MGB So Good? Hint: It's the Surgical Technique It's the Billroth II BP Limb Not Lap Band, Sleeve, RNY
  • 29. Mini-Gastric Bypass Decreases Hunger Dr Rutledge's Survey 2,783 Pts
  • 30. What About the MGB Re: Restriction withouth Obstruction Secondary to Post Gastrectomy Syndrome
  • 31. Mini-Gastric Bypass (MGB): Surgical Rx of Obesity / Diabetes 1. NON-Obstructive Restriction 2. Fatty Food Intolerance w 3. Minimal Malabsorption 4. Decreased Hunger Enforced Healthy Mediterranean Diet
  • 32. Post Gastrectomy Syndrome •Rapid Gastric Emptying •The Bulk Food component draws water into the intestinal lumen causing sudden fluid shifts in the early dumping whereas •Late dumping is caused by a reactive hypoglycemia.
  • 33. MGB: BPLimb + Post Gastrectomy Syndrome • Dog Study 1950, Rapid Gastric Emptying into Small Bowel • Antrectomy and Billroth II Bilio-Pancreatic Limb Bypass Bowel Bypass 5% No effect Bowel Bypass 15% No Effect Bowel Bypass 30% ++Fatty food intolerance, +Fat Malabsorption • ~30% Bypass = MGB
  • 34. Post Gastrectomy Syndrome (PGS) MGB Diet PGS Diet • 6 small feeds • Avoid Sweets, Fats • Avoid High Fat, Fried Food • More Fresh Fruit Vegs • More Dairy (xLactose) • Minimal Liquids • ... • 6 small feeds • Avoid Sweets, Fats • Avoid High Fat, Fried Food • More Fresh Fruit Vegs • More Dairy (xLactose) • Minimal Liquids • ...