This document provides information about genetic engineering and genetically modified organisms (GMOs). It defines genetic engineering as modifying the characteristics of an organism by altering its DNA. GMOs are organisms whose genetic makeup has been artificially modified, usually by inserting genes from another species. The document describes several methods for creating recombinant DNA and GMOs, such as using viruses or metal pellets coated with DNA to insert new genes into cells. It notes that restriction enzymes are necessary to cut DNA for genetic modification. While GMOs are artificially created by humans, they do not occur naturally. The document lists some examples of genetic engineering applications and notes that the safety of GMOs is still debated within the scientific community.