The document discusses the significance of setting in literature, emphasizing that it encompasses not only location but also time, weather, and societal factors that shape characters and actions. It presents examples from different authors, including Art Spiegelman and Marjane Satrapi, to illustrate how graphic novels blend visual elements with narrative to enhance storytelling. Additionally, it highlights how authors like William Faulkner and Anne Beattie use setting to deepen character development, affecting readers' perceptions of the story.