This document discusses the challenges faced by the US Food and Drug Administration (FDA) in meeting its mission and how enterprise search can help address those challenges. It provides an overview of the FDA's information landscape, stakeholder groups, and examples of how search capabilities could help FDA personnel with tasks like product inspections. The document outlines new search functionality needs and best practices for building an effective enterprise search strategy, including getting management buy-in, integrating search technologies with business processes, and being sensitive to different user groups' needs. It also compares the capabilities of the FDA's current search product to those of Discover Technologies' FAST Search Server.