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Seminar 1: Stem Cells
                                         Wilmarie Morales




       During this seminar we were able to learn about recent studies being done with glioma

tumors and stem cell biology. Jessian, our presenter for the day, made the presentation easier

to follow by using images and tables along with his explanations. A few things we learned in the

presentation were that stem cells are biological cells found in all multicellular organisms, that

can divide into, either, diverse specialized cell types or more stem cells. Stem cells can be found

in almost any vital organ in the body, like: the liver, lungs and colon. Stem cells can also be

found in the brain, and are called glia. Gliomas are a type of tumor that start in the brain or

spine. Gliomas have a very strong resemblance to glia cells. Glioblastoma multiform is the most

common and most dangerous of these tumors.


        In the seminar we were informed that these tumors are chemo resistant and therefore

mortal. Currently researchers are trying to find a way to make these tumors susceptible to

chemotherapy. They are trying to do this through the sonic hedgehog pathway and miRNA.

Results of several experiments have confirmed that by adding miRNA to these cells they can

become vulnerable to chemotherapy.


       These results have a profound significance for science. With these findings it may be

possible to find a way to treat and even cure the occurrence of glioma tumors. Not only do

these findings have an impact for further studies done on glioma tumors, but also for future

research that is being done in the fields of oncology (in finding new innovative treatments for
several other cancers) and neurology (using the knowledge of regenerating brain cells to treat

many neurological diseases).

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Wilmarie reflection 1 final

  • 1. Seminar 1: Stem Cells Wilmarie Morales During this seminar we were able to learn about recent studies being done with glioma tumors and stem cell biology. Jessian, our presenter for the day, made the presentation easier to follow by using images and tables along with his explanations. A few things we learned in the presentation were that stem cells are biological cells found in all multicellular organisms, that can divide into, either, diverse specialized cell types or more stem cells. Stem cells can be found in almost any vital organ in the body, like: the liver, lungs and colon. Stem cells can also be found in the brain, and are called glia. Gliomas are a type of tumor that start in the brain or spine. Gliomas have a very strong resemblance to glia cells. Glioblastoma multiform is the most common and most dangerous of these tumors. In the seminar we were informed that these tumors are chemo resistant and therefore mortal. Currently researchers are trying to find a way to make these tumors susceptible to chemotherapy. They are trying to do this through the sonic hedgehog pathway and miRNA. Results of several experiments have confirmed that by adding miRNA to these cells they can become vulnerable to chemotherapy. These results have a profound significance for science. With these findings it may be possible to find a way to treat and even cure the occurrence of glioma tumors. Not only do these findings have an impact for further studies done on glioma tumors, but also for future research that is being done in the fields of oncology (in finding new innovative treatments for
  • 2. several other cancers) and neurology (using the knowledge of regenerating brain cells to treat many neurological diseases).