Current Trends & Developments of Bioinformatics
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This document provides an overview of current trends and developments in bioinformatics. It defines bioinformatics as the application of computer science and information technology to biological data. It discusses how bioinformaticians organize and analyze vast amounts of molecular biology data using algorithms, databases, and computing power. The document also outlines several applications of bioinformatics in fields like experimental molecular biology, genetics, genomics, simulation, and modeling. It notes that bioinformatics has accelerated developments in biomedical engineering and enabled important discoveries in areas like cancer research. Finally, it briefly discusses some bioinformatics databases, research directions involving DNA, RNA and proteins, developments in RNA sequencing technologies, and the growing bioinformatics market impact.
Current Trends & Developments of Bioinformatics
- 1. Current Trends & Developments in Bioinformatics Yousif A. Algabri Algabri@mail.sdu.edu.cn +86 17866931339 Seminar: Introduction to Biomedical Engineering 28.08.2021
- 2. What’s Bioinformatics • The term “Bioinformatics” was invented by Paulien Hogeweg and Ben Hesper in 1970 • Biocomputing: Applications of computer in Bioscience • Explosion of Genomic Data • Access and management of Data What Bioinformaticians do? Create mathematical models, develop dynamic simulations, and perform pattern analyses of biological systems 3
- 3. 4 Components of Bioinformatics Technology Algorithm Analysis Tools Database Computing power
- 4. 5 • To organize vast streams of molecular biology data in an efficient manner • To develop tools that aid in the analysis of such data • To interpret the results accurately and meaningfully • To gain a better understanding of gene analysis, taxonomy, & evolution • To uncover the wealth of Biological information hidden in the mass of sequence, structure, literature and biological data. Why Bioinformatics
- 5. 6 Bioinformatics Medicine Computer Science Math/Physics Biology Disciplines interaction This interaction contributed to the formation of Bioinformatics
- 6. https://bme.srmeaswari.ac.in/page/2/ 8 Applications of Bioinformatics https://bme.srmeaswari.ac.in/page/2/ ▪ In Experimental Molecular Biology ▪ In Genetics and Genomics ▪ In generating Biological Data ▪ Analysis of gene and protein expression ▪ Comparison of genomic data ▪ In Simulation & Modeling of DNA, RNA & Protein
- 7. 9 • Bioinformatics is promising to bring about revolutionary changes in the biomedical sector • Many important discoveries and many solutions to biotechnology and biological problems have been provided by bioinformatics that has accelerated the development of biomedical engineering • It is now being considered as a key to recent cancer discoveries Bioinformatics in BME
- 8. Pacific Biosciences RS 10 Research Directions Protein RNA DNA Studying mutations to determine effects on genes Studying genes expression Examining folding patterns of genes
- 9. Pacific Biosciences RS 11 RNA-seq Developments Northern blot qPCR Microarrays RNA-seq Chromium 10x scRNA-seq
- 10. 12 Bioinformatics Databases 1/3 • Databases are essential for bioinformatics research and applications • Databases covering various information types: for example, • DNA and protein sequences, • molecular structures, • phenotype and biodiversity
- 11. https://www.biotecharticles.com/Bioinformatics-Article/Bioinformatics-Sequence-Databases-3278.html 13 Bioinformatics Databases 2/3 There are huge databases sources, some: Source: https://www.biotecharticles.com/Bioinformatics-Article/Bioinformatics-Sequence-Databases-3278.html
- 12. https://www.biotecharticles.com/Bioinformatics-Article/Bioinformatics-Sequence-Databases-3278.html 14 Bioinformatics Databases 3/3 Source: https://slidetodoc.com/opportunities-in-bioinformatics- presented-by-dr-g-p/
- 13. Some industries have struggled, owing to the COVID-19 pandemic, and some industries have positive impact and one of those is the bioinformatics industry. 15 Bioinformatics Market Ref: https://www.alliedmarketresearch.com/bioinformatics- market Some industries have struggled, owning to the COVID-19 pandemic, and some industries have positive impact and one of those is the bioinformatics industry. LAMEA: Latin America, Middle East and Africa
- 14. 16 Thank you!!!
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