This document provides tips and guidance for non-profits to create a following and engage supporters on Twitter. The key points covered include highlighting pertinent new information from research and studies, empowering supporters by asking for their advice and sharing their content, providing examples of how other non-profits are using Twitter successfully, and reminding non-profits to participate in conversations on Twitter in order to spread their message and engage people. Safety, avoiding private discussions, and maintaining a good follow-to-follower ratio are also addressed.