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Notes 10/20/09

Environmental Effects of Enzyme Activity
      Enzyme saturation
      -Substrate concentration builds up, final product is increased.
                                Increases to maximum concentration.

                                Environmental effects on enzyme activity.
                                -Temperature
                                Higher temperature, rate of reaction rises,
                                        bump into active site more rapidly.
                                              If temperature gets too high,
                                        reaction rate stops entirely.

                                        -pH
                                        Pepsin – Protein, pH of 2 (acidic).

                                        Allosteric Enzyme Activity
                                        -Inhibitor stops enzyme from working,
less product produced.
-Control when enzyme is working and when it’s not.
-Activator molecules make enzyme work, can change active site shape
Enzyme Inhibition
                             -Competitive Inhibition.
                             -Substrate molecules

                           Metabolic pathways
                           -Each enzyme makes a particular change, and by the
                        end, a “team” of enzymes forms a metabolic pathway to
                        produce new molecules.

                            Complex Metabolic Pathways
                        -Mitochondria are the site of cellular respiration.

                            Feedback Inhibition
                        -Metabolic pathway controls itself through feedback
                        inhibition.
                        -End product turns off enzymes, inhibiting production of
                        new molecules, when molecules are not needed to be
                        made.

Chapter Eight (page 125)
The Cell Cycle and Mitosis

Cell division distributes identical sets of chromosomes to daughter cells

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10 20 09 Notes

  • 1. Notes 10/20/09 Environmental Effects of Enzyme Activity Enzyme saturation -Substrate concentration builds up, final product is increased. Increases to maximum concentration. Environmental effects on enzyme activity. -Temperature Higher temperature, rate of reaction rises, bump into active site more rapidly. If temperature gets too high, reaction rate stops entirely. -pH Pepsin – Protein, pH of 2 (acidic). Allosteric Enzyme Activity -Inhibitor stops enzyme from working, less product produced. -Control when enzyme is working and when it’s not. -Activator molecules make enzyme work, can change active site shape
  • 2. Enzyme Inhibition -Competitive Inhibition. -Substrate molecules Metabolic pathways -Each enzyme makes a particular change, and by the end, a “team” of enzymes forms a metabolic pathway to produce new molecules. Complex Metabolic Pathways -Mitochondria are the site of cellular respiration. Feedback Inhibition -Metabolic pathway controls itself through feedback inhibition. -End product turns off enzymes, inhibiting production of new molecules, when molecules are not needed to be made. Chapter Eight (page 125) The Cell Cycle and Mitosis Cell division distributes identical sets of chromosomes to daughter cells