The document presents a novel adaptive algorithm, the Modified Normalized Least Mean Square (MNLMS), to effectively remove power line interference from ECG signals, which are vulnerable to various artifacts. It compares the new algorithm with existing ones in terms of signal-to-noise ratio (SNR), convergence rate, and time complexity, demonstrating MNLMS's superiority in performance despite higher computational complexity. The study emphasizes the importance of accurately filtering artifacts for improved ECG analysis and suggests future research directions, including multistage filtering techniques.