This document analyzes the seismic behavior of a 10-story reinforced concrete frame structure located on sloping ground with different slopes and soil types. The structure is modeled in STAAD Pro and analyzed using the response spectrum method for different seismic zones. Results show that displacement, shear force, and bending moment increase as the slope and seismic zone increase. Displacement also increases as the soil type changes from hard to soft. The study concludes that ground slope and soil type have a significant impact on the seismic response of the structure.