Answers to questions from asymmetric synthesis
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This document contains answers from an expert to questions on asymmetric synthesis. It addresses predicting major products of reactions based on stereochemistry, identifying the appropriate starting material for synthesizing a target molecule via retrosynthesis analysis and mechanism, and determining whether (Z)- or (E)-enolates would form as major products from reactions with lithium diisopropylamine. The expert provides short answers for multiple choice and theoretical questions relating to stereochemistry and asymmetric synthesis.
Answers to questions from asymmetric synthesis
- 1. Answers to Questions from Asymmetric Synthesis 2020 STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 1 Answers to Questions from Asymmetric Synthesis DR. SATYAJIT DEY Department of Chemistry : Tamralipta Mahavidyalaya ______________________________________________________________ Q. No. 1: Predict the major product(s) in each of the following reactions, paying attention to stereochemistry. Answer: A) B) C) D)
- 2. Answers to Questions from Asymmetric Synthesis 2020 STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 2 E) You will get similar stereo-chemical result when methyl group is replaced by phenyl group. Q. No. 2: Which would be the appropriate starting material for the synthesis of the given target molecule with the stereochemistry shown? Explain with retro-synthetic analysis and mechanism. Answer: ______________________________________________________________ _____
- 3. Answers to Questions from Asymmetric Synthesis 2020 STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 3 Q. No. 3: For each of the following molecules, do you expect to form as the major product the (Z)‐ or (E)‐enolate on reaction with lithium diisopropylamine in THF? Answer: A) B) C) ______________________________________________________________