Antibiogram
- 1. JINDAL INSTITUTE OF MEDICAL SCIENCE ANTIBIOGRAM 1/8/2014-1/9/2014 DEPARTMENT OF CLINICAL MICROBIOLOGY & INFECTION CONTROL DR LAL PATH LABS Dr Jayant Balani Jayant.balani@Drlalpathlabs.com 9896539594,09899994898
- 2. Tips on using the antibiogram • Antibiogram is based on the Hospital Flora & antibiotic sensitivity of isolates from Jindal hospital over last 1 month . • Antibiogram is updated at regular intervals(3 months) • Antibiogram can used to guide the empiric therapy in treatment . See the most common isolate from the sample type(Urine,pus etc) ,then see the antibiotic sensitivity of the isolate which may then be used to guide the empiric antibiotic be sensitivity.eg E.coli is the commonest isolate in urine samples from the hospital & Imipenem has the highest sensitivity for E .coli followed by Pipercallin tazobactum & Amikacin. • Antibiotics being used in antibiotic panels are as per Guidelines from CLSI(Clinical laboratries standards Institute),2014.
- 4. Type of isolates(Sputum & E.T) 4 30 26 6 7 1 0 13 25 38 50 E.coli K.Pneum Pseudom Acinetoba S.aureus Enteroco Percentage Percentage
- 7. Number of isolates Gram positive isolates N=number of isolates Gram negative isolates N=number of isolates Staphylococcus aureus 43 Escherichia coli 38 Enterococcus faecalis 05 Klebsiella sp. 57 Streptococcus sp. 02 Pseudomonas sp. 55 Coagulase negative staph.(CONS) 21 Acinetobactor sp. 11 MRSA(Methicillin resistant Staphylococcus) 40 MSSA(Methicillin sensitive Staphylococcus sp.) 30
- 8. GRAM POSITIVE SENSITIVITY Staphylococcus,Enterococcus,Streptococcus n=number of isolates Antibiotic Sensitive (n) Resistant (n) % Antibiotic Sensitive (n) Resistant (n) % Gentamycin 45 25 64% Amikacin 43 27 62% Amoxyclave 35 25 58% Imipenem 43 27 61% Azithromycin 42 28 60% Vancomycin 63 07 90% Erythromycin 48 22 68.5% Linezolid 70 0 100% Clindamycin 60 10 85% Ciprofloxacin 31 39 44%
- 9. Antibiogram(Gram positive isolates) 100 90 85 68 61 60 62 61 64 62 40 86 92 100 0 25 50 75 100 125 Linezolid Vancomycin Clindamycin Erythromycin Imipenem Azithromycin Amikacin Imipenem Gentamycin Amoxyclave Ciprofloxacin mpisulbactam Levofloxacin Teicoplanin % sensitivity
- 10. GRAM NEGATIVE SENSITIVITY E.coli,K.pneumoniae.Citrobactor sp,Enterobactor sp.) n=number of isolates Antibiotic Sensitive (n) Resistant (n) % Antibiotic Sensitive (n) Resistant (n) % Amikacin 62 32 65% Colistin 21 2 91% Ampicillin/su lbactum 39 55 41% Imipenem 112 11 91% Ceftazidime 16 19 45% Cefotaxime 43 57 43% Ciprofloxacin 42 57 42% Ceftriaxone 33 62 34% Cefuroxime 10 60 14% Aztreonam 32 64 33% Meropenem 47 67 41% Piperacillin tazobactum 48 32 60%
- 11. Antibiogram(Gram negative) (E.coli,K.pnem,Citrobactor,Enterobactor) 65 45 42 41 91 43 34 91 60 12 41 14 33 21 0 25 50 75 100 Amikacin Ceftazidime Ciprofloxacin Meropenem Colistin Cefotaxime Ceftriaxone Imipenem n/tazobactum illin/clauvanic illin/sulbactun Cefuroxime Aztreonam Cefipime % sensitivity
- 12. GRAM NEGATIVE SENSITIVITY Pseudomonas sp. n=number of isolates(55) Antibiotic % Sensitivity Antibiotic % Sensitivity Amikacin 88% Cefoperazone /Sulbactum 70% Ceftazidime 88% Imipenem 96% Ciprofloxacin 53% Piperacillin /Tazobactum 67% Meropenem 45% Ticarcillin/Clauva nate 34% Colistin 100% Cefotaxime 54%
- 13. Antibiogram(Pseudomonas sp.) 88 88 55 45 100 54 63 96 67 34 32 48 46 38 0 25 50 75 100 125 Amikacin Ceftazidime Ciprofloxacin Meropenem Colistin Cefotaxime ne/sulbactum Imipenem n/tazobactum illin/clauvanic Tobramycin Levofloxacin Gentamycin Cefepime % sensitivity
- 14. Multidrugresistant organisims(MDROS) • MRSA-4O% • VRE-0 • ESBL-55% • CRE-5%
- 15. THANK YOU