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M.D.(Paed) D.N.B
KIMSDU
KARAD
DR CHANDRASHEKHAR AUNDHAKAR
Apnea of Prematurity
• 7 % of neonates with GA of 34-35weeks
• 15% of neonates with GA of 32-33weeks
• 54% of neonates with GA of 30-31 weeks
• Nearly 100% neonates with GA of < 29 weeks or weight < 1000gm
Apnea of prematurity
Apnea of prematurity
Apnea of prematurity
Apnea is classified into three categories based on the
presence or absence of upper airway obstruction:
Central Apnea
Obstructive Apnea
Mixed Apnea
Apnea of Prematurity
Periodic Breathing Apnea of Prematurity
swallowing
movements
Causes of Apnea ( AllTypes)
• Infection
• Neurological
• Cardiovascular
• Pulmonary
• Inborn Errors of Metabolism
Causes of Apnea ( AllTypes)
• Metabolic
• Hematological
• Gastrointestinal
• Temperature Regulation
• Drugs
Evaluation of a child with apnoea
Investigations
Treatment of apnoea
General measures
Specific measures
Emergency treatment
Key determinants in choosing the appropriate drug.
Methylxanthines
Maior Effects of Methylxanthines
Apnea of prematurity
Methylxanthines
Complications of AOP
Surveillance AOP

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