Apnea of prematurity is common in neonates born before 32 weeks gestation or weighing less than 1000g, with rates as high as 54% in infants born at 30-31 weeks and nearly 100% in infants born below 29 weeks or weighing less than 1000g. Apnea can be classified as central, obstructive, or mixed based on whether there is absence of respiratory effort or upper airway obstruction. Common causes include infection, neurological or cardiovascular issues, pulmonary problems, inborn errors of metabolism, metabolic or hematological conditions, gastrointestinal issues, problems with temperature regulation, and drugs. Evaluation may include investigations and treatment involves general measures as well as specific measures and emergency treatment if needed. Methylxanthines are commonly