This document discusses various applications of differentiation including finding extrema, Rolle's theorem, the mean value theorem, and determining whether a function is increasing or decreasing. It provides examples of using the derivative to find relative extrema, applying Rolle's theorem to show a horizontal tangent exists between two roots, using the mean value theorem to find a point where the tangent line is parallel to the secant line, and determining the intervals where a function is increasing or decreasing using the first derivative test.