Applied Bioinformatics & Chemoinformatics: Techniques, Tools, and Opportunities
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The document presents an overview of bioinformatics and cheminformatics, detailing techniques, tools, and opportunities in the field. It covers topics such as genetic engineering, sequencing, and applications in biotechnology and biopharmaceutical industries, along with current trends and career opportunities. Key resources and databases for bioinformatics are also provided.
Applied Bioinformatics & Chemoinformatics: Techniques, Tools, and Opportunities
- 1. Applied Bioinformatics & Chemoinformatics: Techniques, Tools and Opportunities. FATOKI, Toluwase H. Department of Biochemistry, Federal University of Technology, Akure, Nigeria. +2347032219821 hezekiahfatoki@gmail.com www.linkedin.com/in/hezekiahfatoki www.fheztbioinformatics.wordpress.com
- 2. “None of us is as smart as all of us” – Ken Blanchard. “If you want to go fast, go alone. If you want to go far, go together.” – African Proverb.
- 3. OUTLINES • Introduction to Genetic Engineering • Sequencing: The Next Generation • Introduction to Bioinformatics • Overview of Bioinformatics in Africa • Essential Bioinformatics • Introduction to Database and Tools • Introduction to Chemoinformatics/Pharmacoinformatics • Applications of Bioinformatics • Application in Biotechnology Industries • Application in Biomedical and Biopharmaceuticals Industries • Current Trends and Opportunities • Questions and Answers
- 4. Introduction to Genetic Engineering • The Central Dogma • Concept Maps of Genetic Engineering
- 5. Sequencing: The Next Generation A Life Decoded is the story of this singular milestone in our history, told by the man who through a combination of vision, tenacity, ingenuity, and insight challenged conventional wisdom and refuted his critics to reveal the human genetic code. Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
- 8. Overview of Bioinformatics in Africa
- 9. Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
- 10. Medha Bhagwat, PhD. NIH Library Bioinformatics Support Program
- 11. Essential Bioinformatics • Section I: Introduction And Biological Databases • Section II: Sequence Alignment • Section III: Gene And Promoter Prediction • Section IV: Molecular Phylogenetics • Section V: Structural Bioinformatics • Section VI: Genomics and Proteomics Arthur M. Lesk,(2002). Introduction to Bioinformatics, Oxford University Press, New York
- 12. Introduction to Databases and Tools http://www.cbs.dtu.dk/biotools/ http://molbiol-tools.ca/molecular_biology_freeware.htm http://www.hpc.cam.ac.uk/compbio/software http://bioinformaticssoftwareandtools.co.in/bio_tools.php http://www.bioafrica.net/software.php
- 13. • NCBI: The National Center for Biotechnology Information (USA): http://ncbi.nlm.nih.gov • EBI:The European Bioinformatics Institute: www.ebi.ac.uk • SIB:The Swiss Institute of Bioinformatics Expasy (Expert Protein analysis system): www.expasy.org • Canadian Bioinformatics Resource http://cbr-rbc.nrc-cnrc.gc.ca/
- 14. Chemoinformatics/Pharmacoinformatics Darren Green, (2016). Computational Drug discovery. The computational methods for in silico drug discovery have been broadly categories into two fields bioinformatics and chemoinformatics. In case of bioinformatics, major emphasis is on identification and validation of drug targets, mainly based on functional/structural annotation of genomes. In case of cheminformatics or pharmacoinformatics, major emphasis is on designing of drug molecules or ligands and their interaction with drug targets. Frank K. Brown (1998) defined Chemoinformatics as the mixing of information resources to transform data into information, and information into knowledge, for the intended purpose of making better decisions faster in the arena of drug lead identification and optimization.
- 19. Application in Biotechnology Industries Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
- 21. Application in Biomedical and Biopharmaceuticals Industries Desmond S. T. Nicholl, (2008). An Introduction to Genetic Engineering. Cambridge University Press, New York.
- 22. Jurgen Drews (2000). Drug Discovery: A Historical Perspective, Science/Drug Discovery, vol.287, 1960-1964.
- 24. Current Trends and Opportunities
- 25. Jobs, PhDs and Networks http://blog.biogem.org/2013/03/bioinformatics-carrer-opportunities.html http://www.sib.swiss/about-us/careers http://www.nature.com/naturejobs/science/jobs?q=bioinformatics http://www.bioinformatics.org/jobs/ http://www.linkedin.com/topic/bioinformatics http://www.linkedin.com/topic/computational-biology Online Courses https://www.futurelearn.com https://www.coursera.org Thanks for listening