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Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Lesson OverviewLesson Overview
11.1 The Work of11.1 The Work of
Gregor MendelGregor Mendel
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
THINK ABOUT IT
What is an inheritance?
It is something we each receive from our parents—a contribution that
determines our blood type, the color of our hair, and so much more.
What kind of inheritance makes a person’s face round or hair curly?
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
Where does an organism get its unique characteristics?
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
Where does an organism get its unique characteristics?
An individual’s characteristics are determined by factors that are passed
from one parental generation to the next.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
Every living thing—plant or animal, microbe or human being—has a
set of characteristics inherited from its parent or parents.
The delivery of characteristics from parent to offspring is called
heredity.
The scientific study of heredity, known as genetics, is the key to
understanding what makes each organism unique.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
The modern science of genetics was
founded by an Austrian monk named
Gregor Mendel.
Mendel was in charge of the
monastery garden, where he was
able to do the work that changed
biology forever.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
Mendel carried out his work with
ordinary garden peas, partly
because peas are small and easy
to grow. A single pea plant can
produce hundreds of offspring.
Today we call peas a “model
system.”
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
Scientists use model systems
because they are convenient to study
and may tell us how other organisms,
including humans, actually function.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Experiments of Gregor Mendel
By using peas, Mendel was able to
carry out, in just one or two growing
seasons, experiments that would
have been impossible to do with
humans and that would have taken
decades—if not centuries—to do
with other large animals.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
Mendel knew that the male part of each flower makes pollen, which
contains sperm—the plant’s male reproductive cells.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
Similarly, Mendel knew that the female portion of each flower produces
reproductive cells called eggs.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
During sexual reproduction, male and female reproductive cells join in a
process known as fertilization to produce a new cell.
In peas, this new cell develops into a tiny embryo encased within a seed.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
Pea flowers are normally self-pollinating, which means that sperm cells
fertilize egg cells from within the same flower.
A plant grown from a seed produced by self-pollination inherits all of its
characteristics from the single plant that bore it. In effect, it has a single
parent.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
Mendel’s garden had several stocks of pea plants that were “true-
breeding,” meaning that they were self-pollinating, and would produce
offspring with identical traits to themselves.
In other words, the traits of each successive generation would be the
same.
A trait is a specific characteristic of an individual, such as seed color or
plant height, and may vary from one individual to another.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
Mendel decided to “cross” his stocks of true-breeding plants—he caused
one plant to reproduce with another plant.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
To do this, he had to prevent self-pollination. He did so by cutting away the
pollen-bearing male parts of a flower and then dusting the pollen from a
different plant onto the female part of that flower, as shown in the figure.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
This process, known as cross-pollination, produces a plant that has two
different parents.
Cross-pollination allowed Mendel to breed plants with traits different from
those of their parents and then study the results.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Role of Fertilization
Mendel studied seven different traits of pea plants, each of which had two
contrasting characteristics, such as green seed color or yellow seed color.
Mendel crossed plants with each of the seven contrasting characteristics
and then studied their offspring.
The offspring of crosses between parents with different traits are called
hybrids.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Genes and Alleles
When doing genetic crosses, we call the original pair of plants the P, or
parental, generation.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Genes and Alleles
Their offspring are called the F1, or “first filial,” generation.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Genes and Alleles
For each trait studied in Mendel’s experiments, all the offspring had the
characteristics of only one of their parents, as shown in the table.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Genes and Alleles
In each cross, the nature of the other parent, with regard to each trait,
seemed to have disappeared.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Genes and Alleles
From these results, Mendel drew two conclusions. His first conclusion
formed the basis of our current understanding of inheritance.
An individual’s characteristics are determined by factors that are passed
from one parental generation to the next.
Scientists call the factors that are passed from parent to offspring genes.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Genes and Alleles
Each of the traits Mendel studied was controlled by one gene that occurred
in two contrasting varieties.
These gene variations produced different expressions, or forms, of each
trait.
The different forms of a gene are called alleles.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Dominant and Recessive Traits
Mendel’s second conclusion is called the principle of dominance. This
principle states that some alleles are dominant and others are recessive.
An organism with at least one dominant allele for a particular form of a trait
will exhibit that form of the trait.
An organism with a recessive allele for a particular form of a trait will exhibit
that form only when the dominant allele for the trait is not present.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Dominant and Recessive Traits
In Mendel’s experiments, the allele for tall plants was dominant and the
allele for short plants was recessive.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Dominant and Recessive Traits
In Mendel’s experiments, the allele for tall plants was dominant and the
allele for short plants was recessive. Likewise, the allele for yellow seeds
was dominant over the recessive allele for green seeds
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Segregation
How are different forms of a gene distributed to offspring?
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Segregation
How are different forms of a gene distributed to offspring?
During gamete formation, the alleles for each gene segregate from each
other, so that each gamete carries only one allele for each gene.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Segregation
Mendel wanted to find out what had
happened to the recessive alleles.
To find out, Mendel allowed all seven
kinds of F1 hybrids to self-pollinate. The
offspring of an F1 cross are called the
F2 generation.
The F2 offspring of Mendel’s
experiment are shown.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The F1 Cross
When Mendel compared the F2
plants, he discovered the traits
controlled by the recessive alleles
reappeared in the second
generation.
Roughly one fourth of the F2 plants
showed the trait controlled by the
recessive allele.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Explaining the F1 Cross
Mendel assumed that a dominant
allele had masked the corresponding
recessive allele in the F1 generation.
The reappearance of the recessive
trait in the F2 generation indicated that,
at some point, the allele for shortness
had separated from the allele for
tallness.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Explaining the F1 Cross
How did this separation, or segregation, of alleles occur?
Mendel suggested that the alleles for tallness and shortness in the F1 plants
must have segregated from each other during the formation of the sex
cells, or gametes.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
Let’s assume that each F1 plant—
all of which were tall—inherited
an allele for tallness from its tall
parent and an allele for shortness
from its short parent.
The Formation of Gametes
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Formation of Gametes
When each parent, or F1 adult,
produces gametes, the alleles for
each gene segregate from one
another, so that each gamete
carries only one allele for each
gene.
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
A capital letter represents a
dominant allele. A lowercase letter
represents a recessive allele.
Each F1 plant in Mendel’s cross
produced two kinds of gametes—
those with the allele for tallness (T)
and those with the allele for
shortness (t).
The Formation of Gametes
Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel
The Formation of Gametes
Whenever each of two gametes
carried the t allele and then paired
with the other gamete to produce
an F2 plant, that plant was short.
Every time one or more gametes
carried the T allele and paired
together, they produced a tall plant.
The F2 generation had new
combinations of alleles.

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CVA Biology I - B10vrv4111

  • 1. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Lesson OverviewLesson Overview 11.1 The Work of11.1 The Work of Gregor MendelGregor Mendel
  • 2. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel THINK ABOUT IT What is an inheritance? It is something we each receive from our parents—a contribution that determines our blood type, the color of our hair, and so much more. What kind of inheritance makes a person’s face round or hair curly?
  • 3. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel Where does an organism get its unique characteristics?
  • 4. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel Where does an organism get its unique characteristics? An individual’s characteristics are determined by factors that are passed from one parental generation to the next.
  • 5. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel Every living thing—plant or animal, microbe or human being—has a set of characteristics inherited from its parent or parents. The delivery of characteristics from parent to offspring is called heredity. The scientific study of heredity, known as genetics, is the key to understanding what makes each organism unique.
  • 6. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel The modern science of genetics was founded by an Austrian monk named Gregor Mendel. Mendel was in charge of the monastery garden, where he was able to do the work that changed biology forever.
  • 7. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel Mendel carried out his work with ordinary garden peas, partly because peas are small and easy to grow. A single pea plant can produce hundreds of offspring. Today we call peas a “model system.”
  • 8. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel Scientists use model systems because they are convenient to study and may tell us how other organisms, including humans, actually function.
  • 9. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Experiments of Gregor Mendel By using peas, Mendel was able to carry out, in just one or two growing seasons, experiments that would have been impossible to do with humans and that would have taken decades—if not centuries—to do with other large animals.
  • 10. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization Mendel knew that the male part of each flower makes pollen, which contains sperm—the plant’s male reproductive cells.
  • 11. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization Similarly, Mendel knew that the female portion of each flower produces reproductive cells called eggs.
  • 12. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization During sexual reproduction, male and female reproductive cells join in a process known as fertilization to produce a new cell. In peas, this new cell develops into a tiny embryo encased within a seed.
  • 13. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization Pea flowers are normally self-pollinating, which means that sperm cells fertilize egg cells from within the same flower. A plant grown from a seed produced by self-pollination inherits all of its characteristics from the single plant that bore it. In effect, it has a single parent.
  • 14. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization Mendel’s garden had several stocks of pea plants that were “true- breeding,” meaning that they were self-pollinating, and would produce offspring with identical traits to themselves. In other words, the traits of each successive generation would be the same. A trait is a specific characteristic of an individual, such as seed color or plant height, and may vary from one individual to another.
  • 15. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization Mendel decided to “cross” his stocks of true-breeding plants—he caused one plant to reproduce with another plant.
  • 16. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization To do this, he had to prevent self-pollination. He did so by cutting away the pollen-bearing male parts of a flower and then dusting the pollen from a different plant onto the female part of that flower, as shown in the figure.
  • 17. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization This process, known as cross-pollination, produces a plant that has two different parents. Cross-pollination allowed Mendel to breed plants with traits different from those of their parents and then study the results.
  • 18. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Role of Fertilization Mendel studied seven different traits of pea plants, each of which had two contrasting characteristics, such as green seed color or yellow seed color. Mendel crossed plants with each of the seven contrasting characteristics and then studied their offspring. The offspring of crosses between parents with different traits are called hybrids.
  • 19. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Genes and Alleles When doing genetic crosses, we call the original pair of plants the P, or parental, generation.
  • 20. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Genes and Alleles Their offspring are called the F1, or “first filial,” generation.
  • 21. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Genes and Alleles For each trait studied in Mendel’s experiments, all the offspring had the characteristics of only one of their parents, as shown in the table.
  • 22. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Genes and Alleles In each cross, the nature of the other parent, with regard to each trait, seemed to have disappeared.
  • 23. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Genes and Alleles From these results, Mendel drew two conclusions. His first conclusion formed the basis of our current understanding of inheritance. An individual’s characteristics are determined by factors that are passed from one parental generation to the next. Scientists call the factors that are passed from parent to offspring genes.
  • 24. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Genes and Alleles Each of the traits Mendel studied was controlled by one gene that occurred in two contrasting varieties. These gene variations produced different expressions, or forms, of each trait. The different forms of a gene are called alleles.
  • 25. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Dominant and Recessive Traits Mendel’s second conclusion is called the principle of dominance. This principle states that some alleles are dominant and others are recessive. An organism with at least one dominant allele for a particular form of a trait will exhibit that form of the trait. An organism with a recessive allele for a particular form of a trait will exhibit that form only when the dominant allele for the trait is not present.
  • 26. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Dominant and Recessive Traits In Mendel’s experiments, the allele for tall plants was dominant and the allele for short plants was recessive.
  • 27. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Dominant and Recessive Traits In Mendel’s experiments, the allele for tall plants was dominant and the allele for short plants was recessive. Likewise, the allele for yellow seeds was dominant over the recessive allele for green seeds
  • 28. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Segregation How are different forms of a gene distributed to offspring?
  • 29. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Segregation How are different forms of a gene distributed to offspring? During gamete formation, the alleles for each gene segregate from each other, so that each gamete carries only one allele for each gene.
  • 30. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Segregation Mendel wanted to find out what had happened to the recessive alleles. To find out, Mendel allowed all seven kinds of F1 hybrids to self-pollinate. The offspring of an F1 cross are called the F2 generation. The F2 offspring of Mendel’s experiment are shown.
  • 31. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The F1 Cross When Mendel compared the F2 plants, he discovered the traits controlled by the recessive alleles reappeared in the second generation. Roughly one fourth of the F2 plants showed the trait controlled by the recessive allele.
  • 32. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Explaining the F1 Cross Mendel assumed that a dominant allele had masked the corresponding recessive allele in the F1 generation. The reappearance of the recessive trait in the F2 generation indicated that, at some point, the allele for shortness had separated from the allele for tallness.
  • 33. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Explaining the F1 Cross How did this separation, or segregation, of alleles occur? Mendel suggested that the alleles for tallness and shortness in the F1 plants must have segregated from each other during the formation of the sex cells, or gametes.
  • 34. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel Let’s assume that each F1 plant— all of which were tall—inherited an allele for tallness from its tall parent and an allele for shortness from its short parent. The Formation of Gametes
  • 35. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Formation of Gametes When each parent, or F1 adult, produces gametes, the alleles for each gene segregate from one another, so that each gamete carries only one allele for each gene.
  • 36. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel A capital letter represents a dominant allele. A lowercase letter represents a recessive allele. Each F1 plant in Mendel’s cross produced two kinds of gametes— those with the allele for tallness (T) and those with the allele for shortness (t). The Formation of Gametes
  • 37. Lesson OverviewLesson Overview The Work of Gregor MendelThe Work of Gregor Mendel The Formation of Gametes Whenever each of two gametes carried the t allele and then paired with the other gamete to produce an F2 plant, that plant was short. Every time one or more gametes carried the T allele and paired together, they produced a tall plant. The F2 generation had new combinations of alleles.