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8.3 DNA Replication
KEY CONCEPT
DNA replication copies the genetic information of a
cell.
8.3 DNA Replication
Replication copies the genetic information.

• A single strand of DNA serves as a template for a new
strand.
• The rules of base pairing direct
replication.
• DNA is replicated during the
S (synthesis) stage of the
cell cycle.
• Each body cell gets a
complete set of
identical DNA.
8.3 DNA Replication
Proteins carry out the process of replication.
• DNA serves only as a template.
• Enzymes and other proteins do the actual work of
replication.
– Enzymes unzip the double helix.
– Free-floating nucleotides form hydrogen bonds
with the template strand.
nucleotide

The DNA molecule unzips
in both directions.
8.3 DNA Replication
– DNA polymerase enzymes bond the nucleotides
together to form the double helix.
– Polymerase enzymes form covalent bonds between
nucleotides in the new strand.

new strand

nucleotide

DNA polymerase
8.3 DNA Replication
• Two new molecules of DNA are formed, each with an
original strand and a newly formed strand.

• DNA replication is semiconservative.
original strand

Two molecules of DNA

new strand
8.3 DNA Replication
Replication is fast and accurate.
• DNA replication starts at many points in eukaryotic
chromosomes.

There are many origins of replication in eukaryotic chromosomes.

• DNA polymerases can find and correct errors.

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DNA Replication

  • 1. 8.3 DNA Replication KEY CONCEPT DNA replication copies the genetic information of a cell.
  • 2. 8.3 DNA Replication Replication copies the genetic information. • A single strand of DNA serves as a template for a new strand. • The rules of base pairing direct replication. • DNA is replicated during the S (synthesis) stage of the cell cycle. • Each body cell gets a complete set of identical DNA.
  • 3. 8.3 DNA Replication Proteins carry out the process of replication. • DNA serves only as a template. • Enzymes and other proteins do the actual work of replication. – Enzymes unzip the double helix. – Free-floating nucleotides form hydrogen bonds with the template strand. nucleotide The DNA molecule unzips in both directions.
  • 4. 8.3 DNA Replication – DNA polymerase enzymes bond the nucleotides together to form the double helix. – Polymerase enzymes form covalent bonds between nucleotides in the new strand. new strand nucleotide DNA polymerase
  • 5. 8.3 DNA Replication • Two new molecules of DNA are formed, each with an original strand and a newly formed strand. • DNA replication is semiconservative. original strand Two molecules of DNA new strand
  • 6. 8.3 DNA Replication Replication is fast and accurate. • DNA replication starts at many points in eukaryotic chromosomes. There are many origins of replication in eukaryotic chromosomes. • DNA polymerases can find and correct errors.