What is
Biotechnology?
Chapter 1
Learning Outcomes
Learning Outcomes


Describe the science of biotechnology and identify
its product domains
Learning Outcomes


Describe the science of biotechnology and identify
its product domains



Give examples of careers and job responsibilities
associated with biotechnology
Learning Outcomes


Describe the science of biotechnology and identify
its product domains



Give examples of careers and job responsibilities
associated with biotechnology



Outline the steps in producing and delivering a
product made through recombinant DNA technology
Learning Outcomes


Describe the science of biotechnology and identify
its product domains



Give examples of careers and job responsibilities
associated with biotechnology



Outline the steps in producing and delivering a
product made through recombinant DNA technology



Describe how scientific methodologies are used to
conduct experiments and develop products
Learning Outcomes


Describe the science of biotechnology and identify
its product domains



Give examples of careers and job responsibilities
associated with biotechnology



Outline the steps in producing and delivering a
product made through recombinant DNA technology



Describe how scientific methodologies are used to
conduct experiments and develop products



Apply the strategy for values clarification to
bioethical issues
1.1 Defining Biotechnology

Biotechnology is defined as the study and
manipulation of living things or their
component molecules, cells, tissues, or
organs.
Biotechnology Workers and the
Biotechnology Workplace
Biotechnology Workers and the
Biotechnology Workplace
• Biotechnology Companies - goal is to produce
and sell commercial “for-profit” products
Biotechnology Workers and the
Biotechnology Workplace
• Biotechnology Companies - goal is to produce
and sell commercial “for-profit” products
• Universities and Government Labs - conduct
“pure science” research, nonprofit
Biotechnology Workers and the
Biotechnology Workplace
• Biotechnology Companies - goal is to produce
and sell commercial “for-profit” products
• Universities and Government Labs - conduct
“pure science” research, nonprofit
• Growth in the Biotechnology Industry
5
1.2 The Increasing Variety of
Biotechnology Products

Bioengineered Products
As the methods of manipulating living things
have become more sophisticated, the
number and variety of biological products
have increased at an incredible rate.
Genetically modified organisms – organisms that
contain DNA from another organism and produce new
proteins encoded on the acquired DNA

Gene Engineered Plant. The organism that gets the new genes will then
have the potential to express the new traits coded in the newly acquired genes.
Producing Genetically
Engineered t-PA.

Humans make only a small
amount of human tissue
plasminogen activator (t-PA)
naturally.
By genetically modifying
Chinese hamster ovary
(CHO) cells, scientists can
make large amounts of t-PA
for therapeutic purposes,
such as to clear blood
vessels in the event of a
heart attack or stroke.
Biotechnology Chapter One Lecture- Intro to Biotech
Vocabulary
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
• Polymerase chain reaction (PCR) – a technique that involves
copying short pieces of DNA and then making millions of copies
in a short time
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
• Polymerase chain reaction (PCR) – a technique that involves
copying short pieces of DNA and then making millions of copies
in a short time
• Cloning – method of asexual reproduction that produces
identical organisms
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
• Polymerase chain reaction (PCR) – a technique that involves
copying short pieces of DNA and then making millions of copies
in a short time
• Cloning – method of asexual reproduction that produces
identical organisms
• Fermentation – a process by which, in an oxygen-deprived
environment, a cell converts sugar into lactic acid or ethanol to
create energy
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
• Polymerase chain reaction (PCR) – a technique that involves
copying short pieces of DNA and then making millions of copies
in a short time
• Cloning – method of asexual reproduction that produces
identical organisms
• Fermentation – a process by which, in an oxygen-deprived
environment, a cell converts sugar into lactic acid or ethanol to
create energy
• Proteases – proteins whose function is to break down other
proteins
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
• Polymerase chain reaction (PCR) – a technique that involves
copying short pieces of DNA and then making millions of copies
in a short time
• Cloning – method of asexual reproduction that produces
identical organisms
• Fermentation – a process by which, in an oxygen-deprived
environment, a cell converts sugar into lactic acid or ethanol to
create energy
• Proteases – proteins whose function is to break down other
proteins
• Antibodies – proteins developed by the immune system that
recognize specific molecules (antigens)
Vocabulary
• DNA – abbreviation for deoxyribonucleic acid, a double-stranded
helical molecule that stores genetic information for the
production of all of an organism’s proteins
• Recombinant DNA (rDNA) technology – cutting and
recombining DNA molecules
• Polymerase chain reaction (PCR) – a technique that involves
copying short pieces of DNA and then making millions of copies
in a short time
• Cloning – method of asexual reproduction that produces
identical organisms
• Fermentation – a process by which, in an oxygen-deprived
environment, a cell converts sugar into lactic acid or ethanol to
create energy
• Proteases – proteins whose function is to break down other
proteins
• Antibodies – proteins developed by the immune system that
recognize specific molecules (antigens)
• Pharmaceutical – relating to drugs developed for medical use
Vocabulary
Vocabulary
Vocabulary
• Antibiotics – molecular agents derived from fungi and/
or bacteria that impede the growth and survival of some
Vocabulary
other microorganisms (bacteria killers).
Vocabulary
• Antibiotics – molecular agents derived from fungi and/
or bacteria that impede the growth and survival of some
Vocabulary
other microorganisms (bacteria killers).
• Restriction enzyme – enzyme that cuts DNA at a
specific nucleotide sequence
Vocabulary
• Antibiotics – molecular agents derived from fungi and/
or bacteria that impede the growth and survival of some
Vocabulary
other microorganisms (bacteria killers).
• Restriction enzyme – enzyme that cuts DNA at a
specific nucleotide sequence
• DNA ligase – an enzyme that binds together
disconnected strands of a DNA molecule
Vocabulary
• Antibiotics – molecular agents derived from fungi and/
or bacteria that impede the growth and survival of some
Vocabulary
other microorganisms (bacteria killers).
• Restriction enzyme – enzyme that cuts DNA at a
specific nucleotide sequence
• DNA ligase – an enzyme that binds together
disconnected strands of a DNA molecule
• Recombinant DNA – DNA created by combining DNA
from two or more sources
Vocabulary
• Antibiotics – molecular agents derived from fungi and/
or bacteria that impede the growth and survival of some
Vocabulary
other microorganisms (bacteria killers).
• Restriction enzyme – enzyme that cuts DNA at a
specific nucleotide sequence
• DNA ligase – an enzyme that binds together
disconnected strands of a DNA molecule
• Recombinant DNA – DNA created by combining DNA
from two or more sources
• Genetically modified organisms – organisms that
contain DNA from another organism and produce new
proteins encoded on the acquired DNA
Vocabulary
• Antibiotics – molecular agents derived from fungi and/
or bacteria that impede the growth and survival of some
Vocabulary
other microorganisms (bacteria killers).
• Restriction enzyme – enzyme that cuts DNA at a
specific nucleotide sequence
• DNA ligase – an enzyme that binds together
disconnected strands of a DNA molecule
• Recombinant DNA – DNA created by combining DNA
from two or more sources
• Genetically modified organisms – organisms that
contain DNA from another organism and produce new
proteins encoded on the acquired DNA
• E. coli – a rod-shaped bacterium native to the intestines
of mammals; commonly used in genetics and
biotechnology
Biotechnology Chapter One Lecture- Intro to Biotech
The Human Genome Project
The Human Genome Project
• Determining the human DNA sequence
The Human Genome Project
• Determining the human DNA sequence
• Understanding the function of the
human genetic code
The Human Genome Project
• Determining the human DNA sequence
• Understanding the function of the
human genetic code
• Identifying all of the genes
The Human Genome Project
• Determining the human DNA sequence
• Understanding the function of the
human genetic code
• Identifying all of the genes
• Determining their functions
The Human Genome Project
• Determining the human DNA sequence
• Understanding the function of the
human genetic code
• Identifying all of the genes
• Determining their functions
• Understanding how and when genes are
turned on and off throughout the
lifetime of an individual
1.3 How Companies Select Products to
Manufacture
1.3 How Companies Select Products to
Manufacture
Each biotechnology company usually specializes in a
group of similar products
1.3 How Companies Select Products to
Manufacture
Each biotechnology company usually specializes in a
group of similar products
• Plant products
1.3 How Companies Select Products to
Manufacture
Each biotechnology company usually specializes in a
group of similar products
• Plant products
• Fermentation equipment
1.3 How Companies Select Products to
Manufacture
Each biotechnology company usually specializes in a
group of similar products
• Plant products
• Fermentation equipment
• Viral therapies
1.3 How Companies Select Products to
Manufacture
Each biotechnology company usually specializes in a
group of similar products
• Plant products
• Fermentation equipment
• Viral therapies
• DNA sequencers for research
1.3 How Companies Select Products to
Manufacture
Each biotechnology company usually specializes in a
group of similar products
• Plant products
• Fermentation equipment
• Viral therapies
• DNA sequencers for research
• Enzymes for food processing
1.3 How Companies Select Products to
Manufacture
Developing Ideas for New Products
1.3 How Companies Select Products to
Manufacture
Developing Ideas for New Products
Ideas come from many sources:
1.3 How Companies Select Products to
Manufacture
Developing Ideas for New Products
Ideas come from many sources:
• Discussions lead to new ideas
1.3 How Companies Select Products to
Manufacture
Developing Ideas for New Products
Ideas come from many sources:
• Discussions lead to new ideas
• Reading literature reviews can lead to new
ideas
1.3 How Companies Select Products to
Manufacture
Developing Ideas for New Products
Ideas come from many sources:
• Discussions lead to new ideas
• Reading literature reviews can lead to new
ideas
• Sometimes even daydreaming can lead to
new ideas
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
• Do preliminary data support that the product will work? Will the
product do what the company claims?
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
• Do preliminary data support that the product will work? Will the
product do what the company claims?
• Can patent protection be secured? Can the company prevent
other companies from producing it?
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
• Do preliminary data support that the product will work? Will the
product do what the company claims?
• Can patent protection be secured? Can the company prevent
other companies from producing it?
• Can the company make a profit on the product? How much will it
cost to make it? How much can it be sold for?
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
• Do preliminary data support that the product will work? Will the
product do what the company claims?
• Can patent protection be secured? Can the company prevent
other companies from producing it?
• Can the company make a profit on the product? How much will it
cost to make it? How much can it be sold for?
Situations That End Product Development
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
• Do preliminary data support that the product will work? Will the
product do what the company claims?
• Can patent protection be secured? Can the company prevent
other companies from producing it?
• Can the company make a profit on the product? How much will it
cost to make it? How much can it be sold for?
Situations That End Product Development
• Product development is stopped if testing shows the product is not effective.
A Product Development Plan
Before going into research and development, company
officials must determine whether or not it is worth the
investment of company resources.
Product Development Plan usually includes the following criteria:
• Does the product meet a critical need? Who will use the product?
• Is the market large enough to produce enough sales? How many
customers are there?
• Do preliminary data support that the product will work? Will the
product do what the company claims?
• Can patent protection be secured? Can the company prevent
other companies from producing it?
• Can the company make a profit on the product? How much will it
cost to make it? How much can it be sold for?
Situations That End Product Development
• Product development is stopped if testing shows the product is not effective.
• When this happens, companies can lose millions of dollars and years of
research and development time.




New non-pharmaceutical products must
meet EPA and USDA guidelines.
Pharmaceutical products must pass
clinical trials on human subjects (2-5
years) to receive FDA approval.

Environmental Protection Agency
US Department of Agriculture
Food and Drug Administration

17
Regulations Governing Product Development

New Biotech
Drug Approvals.
Even with all the
government
regulations, the
number of new
drugs approved for
market increased
nearly seven times
in the 10 years
between 1990 and
2000.
19
Vocabulary
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
• Pure science – scientific research whose main purpose is to enrich
the scientific knowledge base
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
• Pure science – scientific research whose main purpose is to enrich
the scientific knowledge base
• Virus – a particle containing a protein coat and genetic materials
(either DNA or RNA) that is not living and requires a host to
replicate
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
• Pure science – scientific research whose main purpose is to enrich
the scientific knowledge base
• Virus – a particle containing a protein coat and genetic materials
(either DNA or RNA) that is not living and requires a host to
replicate
• Applied science – the practice of utilizing scientific knowledge for
practical purposes, including the manufacture of a product
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
• Pure science – scientific research whose main purpose is to enrich
the scientific knowledge base
• Virus – a particle containing a protein coat and genetic materials
(either DNA or RNA) that is not living and requires a host to
replicate
• Applied science – the practice of utilizing scientific knowledge for
practical purposes, including the manufacture of a product
• NIH – abbreviation for National Institutes of Health; the federal
agency that funds and conducts biomedical research
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
• Pure science – scientific research whose main purpose is to enrich
the scientific knowledge base
• Virus – a particle containing a protein coat and genetic materials
(either DNA or RNA) that is not living and requires a host to
replicate
• Applied science – the practice of utilizing scientific knowledge for
practical purposes, including the manufacture of a product
• NIH – abbreviation for National Institutes of Health; the federal
agency that funds and conducts biomedical research
• CDC – abbreviation for Centers for Disease Control and Prevention;
national research center for developing and applying disease
prevention and control, environmental health, and health promotion
and education activities to improve public health
Vocabulary
• Research and development (R&D) – refers to the early stages in
product development that include discovery of the structure and
function of a potential product and initial small-scale production
• Pure science – scientific research whose main purpose is to enrich
the scientific knowledge base
• Virus – a particle containing a protein coat and genetic materials
(either DNA or RNA) that is not living and requires a host to
replicate
• Applied science – the practice of utilizing scientific knowledge for
practical purposes, including the manufacture of a product
• NIH – abbreviation for National Institutes of Health; the federal
agency that funds and conducts biomedical research
• CDC – abbreviation for Centers for Disease Control and Prevention;
national research center for developing and applying disease
prevention and control, environmental health, and health promotion
and education activities to improve public health
• DNA fingerprinting – an experimental technique that is commonly
used to identify individuals by distinguishing their unique DNA code
Vocabulary
Vocabulary
• Reagent – chemical used in an experiment
Vocabulary
• Reagent – chemical used in an experiment
• Efficacy – the ability to yield a desired result or demonstrate that
a product does what it claims to do
Vocabulary
• Reagent – chemical used in an experiment
• Efficacy – the ability to yield a desired result or demonstrate that
a product does what it claims to do
• Clinical trials – a strict series of tests that evaluates the
effectiveness and safety of a medical treatment in humans
Vocabulary
• Reagent – chemical used in an experiment
• Efficacy – the ability to yield a desired result or demonstrate that
a product does what it claims to do
• Clinical trials – a strict series of tests that evaluates the
effectiveness and safety of a medical treatment in humans
• FDA – abbreviation for the Food and Drug Administration; the
federal agency that regulates the use and production of food, feed,
food additives, veterinary drugs, human drugs, and medical
devices
Vocabulary
• Reagent – chemical used in an experiment
• Efficacy – the ability to yield a desired result or demonstrate that
a product does what it claims to do
• Clinical trials – a strict series of tests that evaluates the
effectiveness and safety of a medical treatment in humans
• FDA – abbreviation for the Food and Drug Administration; the
federal agency that regulates the use and production of food, feed,
food additives, veterinary drugs, human drugs, and medical
devices
• Therapeutic – an agent that is used to treat diseases or disorders
Vocabulary
• Reagent – chemical used in an experiment
• Efficacy – the ability to yield a desired result or demonstrate that
a product does what it claims to do
• Clinical trials – a strict series of tests that evaluates the
effectiveness and safety of a medical treatment in humans
• FDA – abbreviation for the Food and Drug Administration; the
federal agency that regulates the use and production of food, feed,
food additives, veterinary drugs, human drugs, and medical
devices
• Therapeutic – an agent that is used to treat diseases or disorders
• EPA – abbreviation for the Environmental Protection Agency; the
federal agency that enforces environmental laws including the use
and production of microorganisms, herbicides, pesticides, and
genetically modified microorganisms
Vocabulary
• Reagent – chemical used in an experiment
• Efficacy – the ability to yield a desired result or demonstrate that
a product does what it claims to do
• Clinical trials – a strict series of tests that evaluates the
effectiveness and safety of a medical treatment in humans
• FDA – abbreviation for the Food and Drug Administration; the
federal agency that regulates the use and production of food, feed,
food additives, veterinary drugs, human drugs, and medical
devices
• Therapeutic – an agent that is used to treat diseases or disorders
• EPA – abbreviation for the Environmental Protection Agency; the
federal agency that enforces environmental laws including the use
and production of microorganisms, herbicides, pesticides, and
genetically modified microorganisms
• USDA – abbreviation for United States Department of Agriculture;
the federal agency that regulates the use and production of plants,
plant products, plant tests, veterinary supplies and medications,
and genetically modified plants and animals
1.4 Doing Biotechnology: Scientific
Methodology in a Research Facility
Conducting an Experiment Using Scientific Methodologies
1.4 Doing Biotechnology: Scientific
Methodology in a Research Facility
Conducting an Experiment Using Scientific Methodologies
1. State a testable scientific question or problem based
on some information or observation.
1.4 Doing Biotechnology: Scientific
Methodology in a Research Facility
Conducting an Experiment Using Scientific Methodologies
1. State a testable scientific question or problem based
on some information or observation.
2. Develop a testable hypothesis.
1.4 Doing Biotechnology: Scientific
Methodology in a Research Facility
Conducting an Experiment Using Scientific Methodologies
1. State a testable scientific question or problem based
on some information or observation.
2. Develop a testable hypothesis.
3. Plan a valid experiment.
1.4 Doing Biotechnology: Scientific
Methodology in a Research Facility
Conducting an Experiment Using Scientific Methodologies
1. State a testable scientific question or problem based
on some information or observation.
2. Develop a testable hypothesis.
3. Plan a valid experiment.
4. Conduct the outlined experiment and collect and
organize the data into tables, charts, graphs, or
graphics.
1.4 Doing Biotechnology: Scientific
Methodology in a Research Facility
Conducting an Experiment Using Scientific Methodologies
1. State a testable scientific question or problem based
on some information or observation.
2. Develop a testable hypothesis.
3. Plan a valid experiment.
4. Conduct the outlined experiment and collect and
organize the data into tables, charts, graphs, or
graphics.
5. Formulate a conclusion based on experimental data
and error analysis.
Develop a testable hypothesis
Data Table and Graph.
Observations and
measurements are
reported in a data table.
Individual trials
(replications) as well as
averages are shown.
Numerical data are shown
in picture form using
graphs.
Sharing Experimental Results with the
Scientific Community

Once an experiment is complete, the
work is reported to others through:
• Publications
• Presentations
• Annual conferences
Vocabulary
Vocabulary
• Data – information gathered from experimentation
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
• Variable – anything that can vary in an experiment; the
independent variable is tested in an experiment to see its effect
on dependent variables
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
• Variable – anything that can vary in an experiment; the
independent variable is tested in an experiment to see its effect
on dependent variables
• Control – experimental trial added to an experiment to ensure
that the experiment was run properly; see positive control and
negative control
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
• Variable – anything that can vary in an experiment; the
independent variable is tested in an experiment to see its effect
on dependent variables
• Control – experimental trial added to an experiment to ensure
that the experiment was run properly; see positive control and
negative control
• Positive control – a group of data that will give predictable
positive results
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
• Variable – anything that can vary in an experiment; the
independent variable is tested in an experiment to see its effect
on dependent variables
• Control – experimental trial added to an experiment to ensure
that the experiment was run properly; see positive control and
negative control
• Positive control – a group of data that will give predictable
positive results
• Negative control – a group of data that will give predictable
negative results
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
• Variable – anything that can vary in an experiment; the
independent variable is tested in an experiment to see its effect
on dependent variables
• Control – experimental trial added to an experiment to ensure
that the experiment was run properly; see positive control and
negative control
• Positive control – a group of data that will give predictable
positive results
• Negative control – a group of data that will give predictable
negative results
• Concentration – the amount of a substance as a proportion of
another substance; usually how much mass in some amount of
volume
Vocabulary
• Data – information gathered from experimentation
• Hypothesis – an educated guess to answer scientific question;
should be testable
• Variable – anything that can vary in an experiment; the
independent variable is tested in an experiment to see its effect
on dependent variables
• Control – experimental trial added to an experiment to ensure
that the experiment was run properly; see positive control and
negative control
• Positive control – a group of data that will give predictable
positive results
• Negative control – a group of data that will give predictable
negative results
• Concentration – the amount of a substance as a proportion of
another substance; usually how much mass in some amount of
volume
• Journals – scientific periodicals or magazines in which scientists
publish their experimental work, findings, or conclusions
1.5 Careers in the Biotechnology Industry
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
• Agricultural
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
• Agricultural
• Environmental
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
• Agricultural
• Environmental

• Applied chemistry
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
• Agricultural
• Environmental

• Applied chemistry
• Physics
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
• Agricultural
• Environmental

• Applied chemistry
• Physics
• Computer science
1.5 Careers in the Biotechnology Industry
• One of the fastest growing commercial industries
• Career opportunities in:
• Bioscience
• Medical
• Agricultural
• Environmental

• Applied chemistry
• Physics
• Computer science

• Industry will be studying DNA sequence for most of
the 21st century
Educational
Requirements
Educational
Requirements
• Bachelor of Science Degree
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
• Sales
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
• Sales
• Marketing
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
• Sales
• Marketing
• Regulatory
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
•
•
•
•

Sales
Marketing
Regulatory
Legal
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
•
•
•
•
•

Sales
Marketing
Regulatory
Legal
Financial
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
•
•
•
•
•
•

Sales
Marketing
Regulatory
Legal
Financial
Human resources
Educational
Requirements
• Bachelor of Science Degree
• Biochemistry
• Molecular biology
• Genetics
• 2-year college degree
• High school specialization
• More advanced degrees
• Master of Science
• Master of Arts
• Doctor of Philosophy
• Postdoctoral research
experience

Nonscientific Positions
Employees in nonscientific positions
must have an interest in and
understanding of the science of
biotechnology.
•
•
•
•
•
•
•

Sales
Marketing
Regulatory
Legal
Financial
Human resources
Administrative staff
Categories of Biotechnology Jobs
Categories of Biotechnology Jobs
• Scientific Positions
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
• Quality Control
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
• Quality Control
• Nonscientific Positions
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
• Quality Control
• Nonscientific Positions
• Information Systems
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
• Quality Control
• Nonscientific Positions
• Information Systems
• Marketing and Sales
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
• Quality Control
• Nonscientific Positions
• Information Systems
• Marketing and Sales
• Regulatory Affairs
Categories of Biotechnology Jobs
• Scientific Positions
• Research and Development
• Manufacturing and Production
• Clinical Research
• Quality Control
• Nonscientific Positions
• Information Systems
• Marketing and Sales
• Regulatory Affairs
• Administration/Legal Affairs
Vocabulary
Vocabulary

• Genome – one entire set of an organism’s
genetic material (from a single cell)
Vocabulary

• Genome – one entire set of an organism’s
genetic material (from a single cell)
• Biochemistry – the study of the chemical
reactions occurring in living things
Vocabulary

• Genome – one entire set of an organism’s
genetic material (from a single cell)
• Biochemistry – the study of the chemical
reactions occurring in living things
• Molecular biology – the study of
molecules that are found in cells
Vocabulary

• Genome – one entire set of an organism’s
genetic material (from a single cell)
• Biochemistry – the study of the chemical
reactions occurring in living things
• Molecular biology – the study of
molecules that are found in cells
• Genetics – the study of genes and how
they are inherited and expressed
1.6 Biotechnology with a Conscience Bioethics
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
• As new situations arise in your life, how do you decide
what is acceptable behavior and what is unacceptable?
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
• As new situations arise in your life, how do you decide
what is acceptable behavior and what is unacceptable?
• How do you decide what is fair and just?
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
• As new situations arise in your life, how do you decide
what is acceptable behavior and what is unacceptable?
• How do you decide what is fair and just?

Moral Standards
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
• As new situations arise in your life, how do you decide
what is acceptable behavior and what is unacceptable?
• How do you decide what is fair and just?

Moral Standards
• Being able to distinguish between right and wrong and to make
decisions based on that knowledge is considered “having good
morals.”
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
• As new situations arise in your life, how do you decide
what is acceptable behavior and what is unacceptable?
• How do you decide what is fair and just?

Moral Standards
• Being able to distinguish between right and wrong and to make
decisions based on that knowledge is considered “having good
morals.”
• The study of moral standards and how they affect conduct is
called ethics.
1.6 Biotechnology with a Conscience Bioethics
• How do we learn what is right and wrong behavior?
• As new situations arise in your life, how do you decide
what is acceptable behavior and what is unacceptable?
• How do you decide what is fair and just?

Moral Standards
• Being able to distinguish between right and wrong and to make
decisions based on that knowledge is considered “having good
morals.”
• The study of moral standards and how they affect conduct is
called ethics.
• New technologies generate ethical questions that cannot be
answered using scientific methods.


Define ethics



Create a code of conduct



Brainstorm bioethical issues or dilemnas

32
Strategy for Values Clarification
Strategy for Values Clarification
• Identify and understand the problem or issue. Learn as
much as possible about the issue.
Strategy for Values Clarification
• Identify and understand the problem or issue. Learn as
much as possible about the issue.
• List all possible solutions to the issue.
Strategy for Values Clarification
• Identify and understand the problem or issue. Learn as
much as possible about the issue.
• List all possible solutions to the issue.
• Identify the pros and cons of adopting each solution.
Examine the consequences of adopting one solution (or
position) as opposed to another. Consider legal, financial,
medical, personal, social, and environmental aspects.
Strategy for Values Clarification
• Identify and understand the problem or issue. Learn as
much as possible about the issue.
• List all possible solutions to the issue.
• Identify the pros and cons of adopting each solution.
Examine the consequences of adopting one solution (or
position) as opposed to another. Consider legal, financial,
medical, personal, social, and environmental aspects.
• Based on the pros and cons for each solution, rank all
solutions from best to worst.
Strategy for Values Clarification
• Identify and understand the problem or issue. Learn as
much as possible about the issue.
• List all possible solutions to the issue.
• Identify the pros and cons of adopting each solution.
Examine the consequences of adopting one solution (or
position) as opposed to another. Consider legal, financial,
medical, personal, social, and environmental aspects.
• Based on the pros and cons for each solution, rank all
solutions from best to worst.
• Decide if the problem is important enough to take a
position. If it is, decide what your position is and be
prepared to describe and defend it.
Questions and Comments?

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Biotechnology Chapter One Lecture- Intro to Biotech

  • 3. Learning Outcomes  Describe the science of biotechnology and identify its product domains
  • 4. Learning Outcomes  Describe the science of biotechnology and identify its product domains  Give examples of careers and job responsibilities associated with biotechnology
  • 5. Learning Outcomes  Describe the science of biotechnology and identify its product domains  Give examples of careers and job responsibilities associated with biotechnology  Outline the steps in producing and delivering a product made through recombinant DNA technology
  • 6. Learning Outcomes  Describe the science of biotechnology and identify its product domains  Give examples of careers and job responsibilities associated with biotechnology  Outline the steps in producing and delivering a product made through recombinant DNA technology  Describe how scientific methodologies are used to conduct experiments and develop products
  • 7. Learning Outcomes  Describe the science of biotechnology and identify its product domains  Give examples of careers and job responsibilities associated with biotechnology  Outline the steps in producing and delivering a product made through recombinant DNA technology  Describe how scientific methodologies are used to conduct experiments and develop products  Apply the strategy for values clarification to bioethical issues
  • 8. 1.1 Defining Biotechnology Biotechnology is defined as the study and manipulation of living things or their component molecules, cells, tissues, or organs.
  • 9. Biotechnology Workers and the Biotechnology Workplace
  • 10. Biotechnology Workers and the Biotechnology Workplace • Biotechnology Companies - goal is to produce and sell commercial “for-profit” products
  • 11. Biotechnology Workers and the Biotechnology Workplace • Biotechnology Companies - goal is to produce and sell commercial “for-profit” products • Universities and Government Labs - conduct “pure science” research, nonprofit
  • 12. Biotechnology Workers and the Biotechnology Workplace • Biotechnology Companies - goal is to produce and sell commercial “for-profit” products • Universities and Government Labs - conduct “pure science” research, nonprofit • Growth in the Biotechnology Industry
  • 13. 5
  • 14. 1.2 The Increasing Variety of Biotechnology Products Bioengineered Products As the methods of manipulating living things have become more sophisticated, the number and variety of biological products have increased at an incredible rate.
  • 15. Genetically modified organisms – organisms that contain DNA from another organism and produce new proteins encoded on the acquired DNA Gene Engineered Plant. The organism that gets the new genes will then have the potential to express the new traits coded in the newly acquired genes.
  • 16. Producing Genetically Engineered t-PA. Humans make only a small amount of human tissue plasminogen activator (t-PA) naturally. By genetically modifying Chinese hamster ovary (CHO) cells, scientists can make large amounts of t-PA for therapeutic purposes, such as to clear blood vessels in the event of a heart attack or stroke.
  • 19. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins
  • 20. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules
  • 21. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules • Polymerase chain reaction (PCR) – a technique that involves copying short pieces of DNA and then making millions of copies in a short time
  • 22. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules • Polymerase chain reaction (PCR) – a technique that involves copying short pieces of DNA and then making millions of copies in a short time • Cloning – method of asexual reproduction that produces identical organisms
  • 23. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules • Polymerase chain reaction (PCR) – a technique that involves copying short pieces of DNA and then making millions of copies in a short time • Cloning – method of asexual reproduction that produces identical organisms • Fermentation – a process by which, in an oxygen-deprived environment, a cell converts sugar into lactic acid or ethanol to create energy
  • 24. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules • Polymerase chain reaction (PCR) – a technique that involves copying short pieces of DNA and then making millions of copies in a short time • Cloning – method of asexual reproduction that produces identical organisms • Fermentation – a process by which, in an oxygen-deprived environment, a cell converts sugar into lactic acid or ethanol to create energy • Proteases – proteins whose function is to break down other proteins
  • 25. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules • Polymerase chain reaction (PCR) – a technique that involves copying short pieces of DNA and then making millions of copies in a short time • Cloning – method of asexual reproduction that produces identical organisms • Fermentation – a process by which, in an oxygen-deprived environment, a cell converts sugar into lactic acid or ethanol to create energy • Proteases – proteins whose function is to break down other proteins • Antibodies – proteins developed by the immune system that recognize specific molecules (antigens)
  • 26. Vocabulary • DNA – abbreviation for deoxyribonucleic acid, a double-stranded helical molecule that stores genetic information for the production of all of an organism’s proteins • Recombinant DNA (rDNA) technology – cutting and recombining DNA molecules • Polymerase chain reaction (PCR) – a technique that involves copying short pieces of DNA and then making millions of copies in a short time • Cloning – method of asexual reproduction that produces identical organisms • Fermentation – a process by which, in an oxygen-deprived environment, a cell converts sugar into lactic acid or ethanol to create energy • Proteases – proteins whose function is to break down other proteins • Antibodies – proteins developed by the immune system that recognize specific molecules (antigens) • Pharmaceutical – relating to drugs developed for medical use
  • 28. Vocabulary • Antibiotics – molecular agents derived from fungi and/ or bacteria that impede the growth and survival of some Vocabulary other microorganisms (bacteria killers).
  • 29. Vocabulary • Antibiotics – molecular agents derived from fungi and/ or bacteria that impede the growth and survival of some Vocabulary other microorganisms (bacteria killers). • Restriction enzyme – enzyme that cuts DNA at a specific nucleotide sequence
  • 30. Vocabulary • Antibiotics – molecular agents derived from fungi and/ or bacteria that impede the growth and survival of some Vocabulary other microorganisms (bacteria killers). • Restriction enzyme – enzyme that cuts DNA at a specific nucleotide sequence • DNA ligase – an enzyme that binds together disconnected strands of a DNA molecule
  • 31. Vocabulary • Antibiotics – molecular agents derived from fungi and/ or bacteria that impede the growth and survival of some Vocabulary other microorganisms (bacteria killers). • Restriction enzyme – enzyme that cuts DNA at a specific nucleotide sequence • DNA ligase – an enzyme that binds together disconnected strands of a DNA molecule • Recombinant DNA – DNA created by combining DNA from two or more sources
  • 32. Vocabulary • Antibiotics – molecular agents derived from fungi and/ or bacteria that impede the growth and survival of some Vocabulary other microorganisms (bacteria killers). • Restriction enzyme – enzyme that cuts DNA at a specific nucleotide sequence • DNA ligase – an enzyme that binds together disconnected strands of a DNA molecule • Recombinant DNA – DNA created by combining DNA from two or more sources • Genetically modified organisms – organisms that contain DNA from another organism and produce new proteins encoded on the acquired DNA
  • 33. Vocabulary • Antibiotics – molecular agents derived from fungi and/ or bacteria that impede the growth and survival of some Vocabulary other microorganisms (bacteria killers). • Restriction enzyme – enzyme that cuts DNA at a specific nucleotide sequence • DNA ligase – an enzyme that binds together disconnected strands of a DNA molecule • Recombinant DNA – DNA created by combining DNA from two or more sources • Genetically modified organisms – organisms that contain DNA from another organism and produce new proteins encoded on the acquired DNA • E. coli – a rod-shaped bacterium native to the intestines of mammals; commonly used in genetics and biotechnology
  • 35. The Human Genome Project
  • 36. The Human Genome Project • Determining the human DNA sequence
  • 37. The Human Genome Project • Determining the human DNA sequence • Understanding the function of the human genetic code
  • 38. The Human Genome Project • Determining the human DNA sequence • Understanding the function of the human genetic code • Identifying all of the genes
  • 39. The Human Genome Project • Determining the human DNA sequence • Understanding the function of the human genetic code • Identifying all of the genes • Determining their functions
  • 40. The Human Genome Project • Determining the human DNA sequence • Understanding the function of the human genetic code • Identifying all of the genes • Determining their functions • Understanding how and when genes are turned on and off throughout the lifetime of an individual
  • 41. 1.3 How Companies Select Products to Manufacture
  • 42. 1.3 How Companies Select Products to Manufacture Each biotechnology company usually specializes in a group of similar products
  • 43. 1.3 How Companies Select Products to Manufacture Each biotechnology company usually specializes in a group of similar products • Plant products
  • 44. 1.3 How Companies Select Products to Manufacture Each biotechnology company usually specializes in a group of similar products • Plant products • Fermentation equipment
  • 45. 1.3 How Companies Select Products to Manufacture Each biotechnology company usually specializes in a group of similar products • Plant products • Fermentation equipment • Viral therapies
  • 46. 1.3 How Companies Select Products to Manufacture Each biotechnology company usually specializes in a group of similar products • Plant products • Fermentation equipment • Viral therapies • DNA sequencers for research
  • 47. 1.3 How Companies Select Products to Manufacture Each biotechnology company usually specializes in a group of similar products • Plant products • Fermentation equipment • Viral therapies • DNA sequencers for research • Enzymes for food processing
  • 48. 1.3 How Companies Select Products to Manufacture Developing Ideas for New Products
  • 49. 1.3 How Companies Select Products to Manufacture Developing Ideas for New Products Ideas come from many sources:
  • 50. 1.3 How Companies Select Products to Manufacture Developing Ideas for New Products Ideas come from many sources: • Discussions lead to new ideas
  • 51. 1.3 How Companies Select Products to Manufacture Developing Ideas for New Products Ideas come from many sources: • Discussions lead to new ideas • Reading literature reviews can lead to new ideas
  • 52. 1.3 How Companies Select Products to Manufacture Developing Ideas for New Products Ideas come from many sources: • Discussions lead to new ideas • Reading literature reviews can lead to new ideas • Sometimes even daydreaming can lead to new ideas
  • 53. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources.
  • 54. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria:
  • 55. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product?
  • 56. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there?
  • 57. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there? • Do preliminary data support that the product will work? Will the product do what the company claims?
  • 58. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there? • Do preliminary data support that the product will work? Will the product do what the company claims? • Can patent protection be secured? Can the company prevent other companies from producing it?
  • 59. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there? • Do preliminary data support that the product will work? Will the product do what the company claims? • Can patent protection be secured? Can the company prevent other companies from producing it? • Can the company make a profit on the product? How much will it cost to make it? How much can it be sold for?
  • 60. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there? • Do preliminary data support that the product will work? Will the product do what the company claims? • Can patent protection be secured? Can the company prevent other companies from producing it? • Can the company make a profit on the product? How much will it cost to make it? How much can it be sold for? Situations That End Product Development
  • 61. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there? • Do preliminary data support that the product will work? Will the product do what the company claims? • Can patent protection be secured? Can the company prevent other companies from producing it? • Can the company make a profit on the product? How much will it cost to make it? How much can it be sold for? Situations That End Product Development • Product development is stopped if testing shows the product is not effective.
  • 62. A Product Development Plan Before going into research and development, company officials must determine whether or not it is worth the investment of company resources. Product Development Plan usually includes the following criteria: • Does the product meet a critical need? Who will use the product? • Is the market large enough to produce enough sales? How many customers are there? • Do preliminary data support that the product will work? Will the product do what the company claims? • Can patent protection be secured? Can the company prevent other companies from producing it? • Can the company make a profit on the product? How much will it cost to make it? How much can it be sold for? Situations That End Product Development • Product development is stopped if testing shows the product is not effective. • When this happens, companies can lose millions of dollars and years of research and development time.
  • 63.   New non-pharmaceutical products must meet EPA and USDA guidelines. Pharmaceutical products must pass clinical trials on human subjects (2-5 years) to receive FDA approval. Environmental Protection Agency US Department of Agriculture Food and Drug Administration 17
  • 64. Regulations Governing Product Development New Biotech Drug Approvals. Even with all the government regulations, the number of new drugs approved for market increased nearly seven times in the 10 years between 1990 and 2000.
  • 65. 19
  • 67. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production
  • 68. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production • Pure science – scientific research whose main purpose is to enrich the scientific knowledge base
  • 69. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production • Pure science – scientific research whose main purpose is to enrich the scientific knowledge base • Virus – a particle containing a protein coat and genetic materials (either DNA or RNA) that is not living and requires a host to replicate
  • 70. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production • Pure science – scientific research whose main purpose is to enrich the scientific knowledge base • Virus – a particle containing a protein coat and genetic materials (either DNA or RNA) that is not living and requires a host to replicate • Applied science – the practice of utilizing scientific knowledge for practical purposes, including the manufacture of a product
  • 71. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production • Pure science – scientific research whose main purpose is to enrich the scientific knowledge base • Virus – a particle containing a protein coat and genetic materials (either DNA or RNA) that is not living and requires a host to replicate • Applied science – the practice of utilizing scientific knowledge for practical purposes, including the manufacture of a product • NIH – abbreviation for National Institutes of Health; the federal agency that funds and conducts biomedical research
  • 72. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production • Pure science – scientific research whose main purpose is to enrich the scientific knowledge base • Virus – a particle containing a protein coat and genetic materials (either DNA or RNA) that is not living and requires a host to replicate • Applied science – the practice of utilizing scientific knowledge for practical purposes, including the manufacture of a product • NIH – abbreviation for National Institutes of Health; the federal agency that funds and conducts biomedical research • CDC – abbreviation for Centers for Disease Control and Prevention; national research center for developing and applying disease prevention and control, environmental health, and health promotion and education activities to improve public health
  • 73. Vocabulary • Research and development (R&D) – refers to the early stages in product development that include discovery of the structure and function of a potential product and initial small-scale production • Pure science – scientific research whose main purpose is to enrich the scientific knowledge base • Virus – a particle containing a protein coat and genetic materials (either DNA or RNA) that is not living and requires a host to replicate • Applied science – the practice of utilizing scientific knowledge for practical purposes, including the manufacture of a product • NIH – abbreviation for National Institutes of Health; the federal agency that funds and conducts biomedical research • CDC – abbreviation for Centers for Disease Control and Prevention; national research center for developing and applying disease prevention and control, environmental health, and health promotion and education activities to improve public health • DNA fingerprinting – an experimental technique that is commonly used to identify individuals by distinguishing their unique DNA code
  • 75. Vocabulary • Reagent – chemical used in an experiment
  • 76. Vocabulary • Reagent – chemical used in an experiment • Efficacy – the ability to yield a desired result or demonstrate that a product does what it claims to do
  • 77. Vocabulary • Reagent – chemical used in an experiment • Efficacy – the ability to yield a desired result or demonstrate that a product does what it claims to do • Clinical trials – a strict series of tests that evaluates the effectiveness and safety of a medical treatment in humans
  • 78. Vocabulary • Reagent – chemical used in an experiment • Efficacy – the ability to yield a desired result or demonstrate that a product does what it claims to do • Clinical trials – a strict series of tests that evaluates the effectiveness and safety of a medical treatment in humans • FDA – abbreviation for the Food and Drug Administration; the federal agency that regulates the use and production of food, feed, food additives, veterinary drugs, human drugs, and medical devices
  • 79. Vocabulary • Reagent – chemical used in an experiment • Efficacy – the ability to yield a desired result or demonstrate that a product does what it claims to do • Clinical trials – a strict series of tests that evaluates the effectiveness and safety of a medical treatment in humans • FDA – abbreviation for the Food and Drug Administration; the federal agency that regulates the use and production of food, feed, food additives, veterinary drugs, human drugs, and medical devices • Therapeutic – an agent that is used to treat diseases or disorders
  • 80. Vocabulary • Reagent – chemical used in an experiment • Efficacy – the ability to yield a desired result or demonstrate that a product does what it claims to do • Clinical trials – a strict series of tests that evaluates the effectiveness and safety of a medical treatment in humans • FDA – abbreviation for the Food and Drug Administration; the federal agency that regulates the use and production of food, feed, food additives, veterinary drugs, human drugs, and medical devices • Therapeutic – an agent that is used to treat diseases or disorders • EPA – abbreviation for the Environmental Protection Agency; the federal agency that enforces environmental laws including the use and production of microorganisms, herbicides, pesticides, and genetically modified microorganisms
  • 81. Vocabulary • Reagent – chemical used in an experiment • Efficacy – the ability to yield a desired result or demonstrate that a product does what it claims to do • Clinical trials – a strict series of tests that evaluates the effectiveness and safety of a medical treatment in humans • FDA – abbreviation for the Food and Drug Administration; the federal agency that regulates the use and production of food, feed, food additives, veterinary drugs, human drugs, and medical devices • Therapeutic – an agent that is used to treat diseases or disorders • EPA – abbreviation for the Environmental Protection Agency; the federal agency that enforces environmental laws including the use and production of microorganisms, herbicides, pesticides, and genetically modified microorganisms • USDA – abbreviation for United States Department of Agriculture; the federal agency that regulates the use and production of plants, plant products, plant tests, veterinary supplies and medications, and genetically modified plants and animals
  • 82. 1.4 Doing Biotechnology: Scientific Methodology in a Research Facility Conducting an Experiment Using Scientific Methodologies
  • 83. 1.4 Doing Biotechnology: Scientific Methodology in a Research Facility Conducting an Experiment Using Scientific Methodologies 1. State a testable scientific question or problem based on some information or observation.
  • 84. 1.4 Doing Biotechnology: Scientific Methodology in a Research Facility Conducting an Experiment Using Scientific Methodologies 1. State a testable scientific question or problem based on some information or observation. 2. Develop a testable hypothesis.
  • 85. 1.4 Doing Biotechnology: Scientific Methodology in a Research Facility Conducting an Experiment Using Scientific Methodologies 1. State a testable scientific question or problem based on some information or observation. 2. Develop a testable hypothesis. 3. Plan a valid experiment.
  • 86. 1.4 Doing Biotechnology: Scientific Methodology in a Research Facility Conducting an Experiment Using Scientific Methodologies 1. State a testable scientific question or problem based on some information or observation. 2. Develop a testable hypothesis. 3. Plan a valid experiment. 4. Conduct the outlined experiment and collect and organize the data into tables, charts, graphs, or graphics.
  • 87. 1.4 Doing Biotechnology: Scientific Methodology in a Research Facility Conducting an Experiment Using Scientific Methodologies 1. State a testable scientific question or problem based on some information or observation. 2. Develop a testable hypothesis. 3. Plan a valid experiment. 4. Conduct the outlined experiment and collect and organize the data into tables, charts, graphs, or graphics. 5. Formulate a conclusion based on experimental data and error analysis.
  • 88. Develop a testable hypothesis
  • 89. Data Table and Graph. Observations and measurements are reported in a data table. Individual trials (replications) as well as averages are shown. Numerical data are shown in picture form using graphs.
  • 90. Sharing Experimental Results with the Scientific Community Once an experiment is complete, the work is reported to others through: • Publications • Presentations • Annual conferences
  • 92. Vocabulary • Data – information gathered from experimentation
  • 93. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable
  • 94. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable • Variable – anything that can vary in an experiment; the independent variable is tested in an experiment to see its effect on dependent variables
  • 95. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable • Variable – anything that can vary in an experiment; the independent variable is tested in an experiment to see its effect on dependent variables • Control – experimental trial added to an experiment to ensure that the experiment was run properly; see positive control and negative control
  • 96. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable • Variable – anything that can vary in an experiment; the independent variable is tested in an experiment to see its effect on dependent variables • Control – experimental trial added to an experiment to ensure that the experiment was run properly; see positive control and negative control • Positive control – a group of data that will give predictable positive results
  • 97. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable • Variable – anything that can vary in an experiment; the independent variable is tested in an experiment to see its effect on dependent variables • Control – experimental trial added to an experiment to ensure that the experiment was run properly; see positive control and negative control • Positive control – a group of data that will give predictable positive results • Negative control – a group of data that will give predictable negative results
  • 98. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable • Variable – anything that can vary in an experiment; the independent variable is tested in an experiment to see its effect on dependent variables • Control – experimental trial added to an experiment to ensure that the experiment was run properly; see positive control and negative control • Positive control – a group of data that will give predictable positive results • Negative control – a group of data that will give predictable negative results • Concentration – the amount of a substance as a proportion of another substance; usually how much mass in some amount of volume
  • 99. Vocabulary • Data – information gathered from experimentation • Hypothesis – an educated guess to answer scientific question; should be testable • Variable – anything that can vary in an experiment; the independent variable is tested in an experiment to see its effect on dependent variables • Control – experimental trial added to an experiment to ensure that the experiment was run properly; see positive control and negative control • Positive control – a group of data that will give predictable positive results • Negative control – a group of data that will give predictable negative results • Concentration – the amount of a substance as a proportion of another substance; usually how much mass in some amount of volume • Journals – scientific periodicals or magazines in which scientists publish their experimental work, findings, or conclusions
  • 100. 1.5 Careers in the Biotechnology Industry
  • 101. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries
  • 102. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in:
  • 103. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience
  • 104. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical
  • 105. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical • Agricultural
  • 106. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical • Agricultural • Environmental
  • 107. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical • Agricultural • Environmental • Applied chemistry
  • 108. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical • Agricultural • Environmental • Applied chemistry • Physics
  • 109. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical • Agricultural • Environmental • Applied chemistry • Physics • Computer science
  • 110. 1.5 Careers in the Biotechnology Industry • One of the fastest growing commercial industries • Career opportunities in: • Bioscience • Medical • Agricultural • Environmental • Applied chemistry • Physics • Computer science • Industry will be studying DNA sequence for most of the 21st century
  • 113. Educational Requirements • Bachelor of Science Degree • Biochemistry
  • 114. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology
  • 115. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics
  • 116. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree
  • 117. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization
  • 118. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees
  • 119. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science
  • 120. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts
  • 121. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy
  • 122. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience
  • 123. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions
  • 124. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology.
  • 125. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • Sales
  • 126. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • Sales • Marketing
  • 127. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • Sales • Marketing • Regulatory
  • 128. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • • • • Sales Marketing Regulatory Legal
  • 129. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • • • • • Sales Marketing Regulatory Legal Financial
  • 130. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • • • • • • Sales Marketing Regulatory Legal Financial Human resources
  • 131. Educational Requirements • Bachelor of Science Degree • Biochemistry • Molecular biology • Genetics • 2-year college degree • High school specialization • More advanced degrees • Master of Science • Master of Arts • Doctor of Philosophy • Postdoctoral research experience Nonscientific Positions Employees in nonscientific positions must have an interest in and understanding of the science of biotechnology. • • • • • • • Sales Marketing Regulatory Legal Financial Human resources Administrative staff
  • 133. Categories of Biotechnology Jobs • Scientific Positions
  • 134. Categories of Biotechnology Jobs • Scientific Positions • Research and Development
  • 135. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production
  • 136. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research
  • 137. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research • Quality Control
  • 138. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research • Quality Control • Nonscientific Positions
  • 139. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research • Quality Control • Nonscientific Positions • Information Systems
  • 140. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research • Quality Control • Nonscientific Positions • Information Systems • Marketing and Sales
  • 141. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research • Quality Control • Nonscientific Positions • Information Systems • Marketing and Sales • Regulatory Affairs
  • 142. Categories of Biotechnology Jobs • Scientific Positions • Research and Development • Manufacturing and Production • Clinical Research • Quality Control • Nonscientific Positions • Information Systems • Marketing and Sales • Regulatory Affairs • Administration/Legal Affairs
  • 144. Vocabulary • Genome – one entire set of an organism’s genetic material (from a single cell)
  • 145. Vocabulary • Genome – one entire set of an organism’s genetic material (from a single cell) • Biochemistry – the study of the chemical reactions occurring in living things
  • 146. Vocabulary • Genome – one entire set of an organism’s genetic material (from a single cell) • Biochemistry – the study of the chemical reactions occurring in living things • Molecular biology – the study of molecules that are found in cells
  • 147. Vocabulary • Genome – one entire set of an organism’s genetic material (from a single cell) • Biochemistry – the study of the chemical reactions occurring in living things • Molecular biology – the study of molecules that are found in cells • Genetics – the study of genes and how they are inherited and expressed
  • 148. 1.6 Biotechnology with a Conscience Bioethics
  • 149. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior?
  • 150. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior? • As new situations arise in your life, how do you decide what is acceptable behavior and what is unacceptable?
  • 151. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior? • As new situations arise in your life, how do you decide what is acceptable behavior and what is unacceptable? • How do you decide what is fair and just?
  • 152. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior? • As new situations arise in your life, how do you decide what is acceptable behavior and what is unacceptable? • How do you decide what is fair and just? Moral Standards
  • 153. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior? • As new situations arise in your life, how do you decide what is acceptable behavior and what is unacceptable? • How do you decide what is fair and just? Moral Standards • Being able to distinguish between right and wrong and to make decisions based on that knowledge is considered “having good morals.”
  • 154. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior? • As new situations arise in your life, how do you decide what is acceptable behavior and what is unacceptable? • How do you decide what is fair and just? Moral Standards • Being able to distinguish between right and wrong and to make decisions based on that knowledge is considered “having good morals.” • The study of moral standards and how they affect conduct is called ethics.
  • 155. 1.6 Biotechnology with a Conscience Bioethics • How do we learn what is right and wrong behavior? • As new situations arise in your life, how do you decide what is acceptable behavior and what is unacceptable? • How do you decide what is fair and just? Moral Standards • Being able to distinguish between right and wrong and to make decisions based on that knowledge is considered “having good morals.” • The study of moral standards and how they affect conduct is called ethics. • New technologies generate ethical questions that cannot be answered using scientific methods.
  • 156.  Define ethics  Create a code of conduct  Brainstorm bioethical issues or dilemnas 32
  • 157. Strategy for Values Clarification
  • 158. Strategy for Values Clarification • Identify and understand the problem or issue. Learn as much as possible about the issue.
  • 159. Strategy for Values Clarification • Identify and understand the problem or issue. Learn as much as possible about the issue. • List all possible solutions to the issue.
  • 160. Strategy for Values Clarification • Identify and understand the problem or issue. Learn as much as possible about the issue. • List all possible solutions to the issue. • Identify the pros and cons of adopting each solution. Examine the consequences of adopting one solution (or position) as opposed to another. Consider legal, financial, medical, personal, social, and environmental aspects.
  • 161. Strategy for Values Clarification • Identify and understand the problem or issue. Learn as much as possible about the issue. • List all possible solutions to the issue. • Identify the pros and cons of adopting each solution. Examine the consequences of adopting one solution (or position) as opposed to another. Consider legal, financial, medical, personal, social, and environmental aspects. • Based on the pros and cons for each solution, rank all solutions from best to worst.
  • 162. Strategy for Values Clarification • Identify and understand the problem or issue. Learn as much as possible about the issue. • List all possible solutions to the issue. • Identify the pros and cons of adopting each solution. Examine the consequences of adopting one solution (or position) as opposed to another. Consider legal, financial, medical, personal, social, and environmental aspects. • Based on the pros and cons for each solution, rank all solutions from best to worst. • Decide if the problem is important enough to take a position. If it is, decide what your position is and be prepared to describe and defend it.