Bioterrorism involves the intentional release of biological agents like viruses, bacteria, or toxins to cause disease or death in humans, animals, or plants. It has occurred throughout history, such as when the British distributed smallpox-infected blankets to Native Americans in the 18th century. Biological weapons are categorized based on their contagiousness and lethality. Category A agents like anthrax, smallpox, and plague are highly contagious and lethal. While biological attacks are difficult to carry out and predict, strengthening public health measures like disease monitoring and drug development can help address this threat.